Intracranial Gliofibroma: A Case Report and Review of the Literature

Table 1

Clinical data and outcomes of patients with gliofibroma in the pediatric population published in the literature and the case presented here.

Author/reference	Year	Age		Sex	Location	Surgery	Adjuvant therapy	Outcome (time of follow-up)
Friede [1]	1978	3.9 yrs		F	Brainstem	Autopsy	RT; CH	Died (3 mo)
Iglesias et al. [2]	1984	11 d		M	Spinal cord	PR	None	Alive (4 yrs)
Reinhardt and Nahser [9]	1984	16 yrs		F	Hemispheric	CR	None	Alive (6 mo)
Snipes et al. [7]	1991	<2 mo		F	Posterior fossa/thalamus	PR	None	Died (16 mo)
Vázquez et al. [8]	1991	9 yrs		F	Spinal cord	PR	RT	Died (18 mo)
Vázquez et al. [8]	1991	5.6 yrs		M	Spinal cord	PR	RT	Alive (2.5 yrs)
Vázquez et al. [8]	1991	11 mo		F	Hemispheric	PR	None	Alive (2 yrs)
Schober et al. [6]	1992	18 yrs		M	Hemispheric	CR	ND	ND
Iglesias-Rozas et al.; [23]	1992	1.2 yrs		F	Hemispheric	CR	None	Alive (18 mo)
Rushing et al. [15]	1993	6 mo		F	IV ventricle	CR	None	Alive (2 yrs)
Cerda-Nicolas and Kepes [10]	1993	9 yrs		M	Hemispheric	CR	ND	Alive (5.5 mo)
Cerda-Nicolas and Kepes [10]	1993	4 yrs		F	IV ventricle	Bx	ND	ND
Windisch et al. [24]	1995	5 mo		M	Spinal cord	PR	None	Alive (7 mo)
Caldemeyer et al. [21]	1995	8 yrs		M	Hemispheric	ND	CH	Alive (ND)
Caldemeyer et al. [21]	1995	6 mo		F	Cerebellum	CR	None	Alive (ND)
Prayson [25]	1996	3 mo		M	Hemispheric	PR	None	Alive (3 yrs)
Mölenkamp et al. [26]	1998	ND		ND	ND	ND	ND	ND
Matsumura et al. [12]	2002	12 yrs		F	Spinal cord	CR	ND	Alive (2.9 yrs)
Suárez et al. [18]	2004	ND		ND	ND	Bx	CH	Alive (3 yrs)
Erguvan-Önal et al.; [27]	2004	16 yrs		M	Hemispheric	CR	None	Alive (14 mo)
Deb et al. [28]	2006	15 yrs		ND	Brainstem	CR	None	ND
Goyal et al. [14]	2007	8 yrs		M	Hemispheric	PR	RT; CH	Alive (1 yrs)
Goyal et al. [14]	2007	15 yrs		F	III ventricle	PR/CR	RT^(*); CH^(*)	Alive (2 yrs)
Sarkar et al. [19]	2009	3 mo		F	Lateral ventricles/III ventricle	Bx	None	Alive (10 yrs)
Altamirano et al. [22]	2011	7 yrs		F	Thalamus/mesencephalon	PR	RT; CH	Died (4 mo)
Gargano et al., this report	2013		10.7 yrs	F	Hemispheric	CR	None	Alive (2 yrs)

ND: no data; yrs: years; mo: months; d: days; F: female; M: male; CR: complete resection; PR: partial resection; Bx: biopsy; RT: radiation therapy; CH: chemotherapy. (∗)after second surgery.