Case Report

Intravascular Large B-Cell Lymphoma Presenting as Interstitial Lung Disease

Figure 2

At autopsy, many of the organs showed involvement by intravascular diffuse large B-cell lymphoma. The alveolar wall showed large atypical cells in the capillaries (a) that were positive for CD20 (inset). Within the arteriole wall of the lung were these atypical cells as well (b). The myocardium also showed these large atypical cells in the vessel lumen (c). Retrospective evaluation of the bone marrow also showed inconspicuous large cells in clusters (d) highlighted with CD20 (inset).
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(a)
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(b)
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(c)
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(d)