Invasive Mucinous Adenocarcinoma Associated with Adjacent Sessile Serrated Lesion of the Appendix Vermiform: A Case Report

Table 1

Immunohistochemical features comparing adenocarcinoma and SSL.

Antibody	Clone	Vendor	Dilution	Adenocarcinoma	SSL
p53^a	DO-7	DAKO	1 : 50	Negative	Negative
MUC2^b	Ccp58	Leica	1 : 20	Positive	Positive
MUC5A/C^b	CLH2	Leica	1 : 100	Positive	Positive
MUC6^b	CLH5	Leica	1 : 100	Negative	Negative
MLH-1^c	G168-728	Cell Marque	1 : 200	None (or weak)	None
MSH-2^c	G219-1129	Cell Marque	1 : 1	Strong	Weak
B-catenin^d	H-102	Santa-Cruz	1 : 200	Negative	Negative

aNuclear staining in more than 10% of the lesion was considered positive.
^bAny definitive cytoplasmic reactivity was considered positive.
^cMore than 10% of positive staining cell was classified as weak, moderate, and strong, according to the staining intensity.
^dAberrant nuclear localization was considered positive.