Case Report

Retiform Sertoli-Leydig Cell Tumor in a 38-Year-Old Woman: A Case Report, Retrospective Review, and Review of Current Literature

Table 1

Summary of immunohistochemical profile of the tumor by component.

Positive stainsNegative stains

Solid areas (Sertoli cells) Pancytokeratin (strong, diffuse)CK7
Beta-catenin (nuclear and cytoplasmic)Glypican-3
CalretininCyclin-D1
InhibinNapsin
WT-1 (nuclear staining)CK20
ERD2-40
PRp53
AFP
CD10
HEPAR-1
Arginase

Leydig cellsInhibin (strong)Pancytokeratin
CalretininCK7
Beta-catenin (nuclear and cytoplasmic)ER
PR
Glypican-3
Cyclin-D1
Napsin
CK20
D2-40
p53
AFP
CD10
HEPAR-1
Arginase

Retiform areasPancytokeratin (strong)ER
Beta-catenin (nuclear and cytoplasmic)Glypican-3
CalretininCyclin-D1
WT-1 (nuclear staining)Napsin
PRCK20
CK7 (weak, focal)D2-40
Inhibin (weak)p53
AFP
CD10
HEPAR-1
Arginase