Case Report
Retiform Sertoli-Leydig Cell Tumor in a 38-Year-Old Woman: A Case Report, Retrospective Review, and Review of Current Literature
Table 1
Summary of immunohistochemical profile of the tumor by component.
| | Positive stains | Negative stains |
| Solid areas (Sertoli cells) | Pancytokeratin (strong, diffuse) | CK7 | Beta-catenin (nuclear and cytoplasmic) | Glypican-3 | Calretinin | Cyclin-D1 | Inhibin | Napsin | WT-1 (nuclear staining) | CK20 | ER | D2-40 | PR | p53 | | AFP | | CD10 | | HEPAR-1 | | Arginase |
| Leydig cells | Inhibin (strong) | Pancytokeratin | Calretinin | CK7 | Beta-catenin (nuclear and cytoplasmic) | ER | | PR | | Glypican-3 | | Cyclin-D1 | | Napsin | | CK20 | | D2-40 | | p53 | | AFP | | CD10 | | HEPAR-1 | | Arginase |
| Retiform areas | Pancytokeratin (strong) | ER | Beta-catenin (nuclear and cytoplasmic) | Glypican-3 | Calretinin | Cyclin-D1 | WT-1 (nuclear staining) | Napsin | PR | CK20 | CK7 (weak, focal) | D2-40 | Inhibin (weak) | p53 | | AFP | | CD10 | | HEPAR-1 | | Arginase |
|
|