Case Report
Synchronous Seminoma in Abdominopelvic and Inguinal Testes: A Rare Presentation with Unusual Morphology
| Author | Age & sex | Location | Size | TM (LDH β-hCG α-AFP) | Gross findings | Histomorphology | Stage | Treatment | F/U |
| Darabi and Barzegarnejad (2004) | 23 M | Intra-abdominal (pelvic) | Big (NM) | NM, Nor, ↑ | NM | Classic seminoma and embryonal carcinoma | II | Bilateral orchidectomy + RT | NM | Agrawal et al. (2010) | 23 M | Intra-abdominal (both) | Big (NM) | Nor | Hetero (hemorrhage + necrosis) | Pure seminoma | IA | Surgery & 4CT (BEP) | 5 yr | García Morúa et al. (2010) | 44 M | Inguinal and pelvic cavity | 15 & 10 | 601, 11.8, 5.08 | Hetero (solid & cystic) | Pure classic testicular seminoma | I & II | Bilateral orchiectomy (NM further) | NM | Kumar et al. (2012) | 30 M | Intra-abdominal (left iliac fossa and post to UB) | 6.5 & 7.4 | 1257 0.38 2.02 | No areas of hemorrhage/necrosis | Poorly diff. sem | I | Surgery & 4CT (BEP) | 8 moths | Singh et al. (2012) | 26 M | Left iliac fossa and lumbar region (ext into inguinal canal) | 10 & 4.0 | 378, 1.49, 3.26 | Hetero (cystic areas and calcification) | Seminoma and GCNIS | IA | Surgery & 3CT (BEP) | NM | Seetharam et al. (2014) | 28 M (heterosexual) | Intra-abdominal (lumbar region) | 13.4 & 9.6 | 2890, Nor, Nor | Homogenous | Pure seminoma | I | Surgery & 4 CT (BEP) | 6 mths | Ghartimagar et al. (2014) | 40 M | Abdominopelvic | 12.2 & 10.7 | 519, 1.1, 9.2 | Homogenous | Classical seminoma | NM | Surgery & 4 CT (BEP) | 8 mths | Rao et al. (2015) | 37 M | Bilateral inguinal | 7.0 & 1.0 | 210, 4.07, 0.2 | Solid, grey white to yellow, homogenous | Seminoma | I | Bilateral orchiectomy | NM | Afsar et al. (2016) | 36 M | Bilateral inguinal | 5.5 & 1.0 | NM | Yellow homogenous | Seminoma | NM | Bilateral orchiectomy | NM | Present case (2016) | 56 M | Intra-abdominal and inguinal | 9.0 & 3.0 | 790, 2.6, 2.8 | Hetero | Seminoma with anaplastic features | IB | Bilateral orchiectomy & CT | 9 mths |
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TM: tumor markers. LDH: lactate dehydrogenase (U/L). β-hCG: beta-human chorionic gonadotrophin (mIU/ml). α-AFP: alpha-fetoprotein level (ng/ml). F/U: follow-up (with no recurrence). NM: not mentioned. Nor: normal. Hetero: heterogenous. CT: chemotherapy. BEP: bleomycin, etoposide, and cisplatin.
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