PAX8 Distinguishes Diffuse Large B-Cell Lymphoma Mimicking Sarcoma

Figure 1

Morphologic features of the original dura/calvarium lesion. (a–c) H&E staining demonstrates a malignant spindle and epithelioid cell neoplasm with increased mitotic activity ((c), arrow) and necrosis (not shown). A large panel of immunostains, including markers of both epithelial and mesenchymal differentiation, was negative, except for focal expression of SMA (inset).

(a)

(b)

(c)