SMARCA4-Deficient Carcinoma of Unknown Primary Presenting with Fatal Paraneoplastic Hypercalcemia in a Heart Transplant Recipient: First Report in a Male Patient

<div>(a) Liver biopsy showed tumor tissue diffusely infiltrating the liver parenchyma (normal liver is seen in lower left field). (b) Higher magnification showed anaplastic large epithelioid cells with prominent nucleoli. (c) Scattered rhabdoid inclusions are seen (arrows) as well as small cytoplasmic vacuoles possibly suggestive of abortive glandular differentiation. (d) In other areas, hemorrhage and spindling might be mistaken for a vascular neoplasm.</div>

Case Reports in Pathology

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Figure 2: SMARCA4-Deficient Carcinoma of Unknown Primary Presenting with Fatal Paraneoplastic Hypercalcemia in a Heart Transplant Recipient: First Report in a Male Patient 

Figure 2 | SMARCA4-Deficient Carcinoma of Unknown Primary Presenting with Fatal Paraneoplastic Hypercalcemia in a Heart Transplant Recipient: First Report in a Male Patient 