Congenital Central Hypothyroidism due to a Homozygous Mutation in the <i>TSHβ</i> Subunit Gene

<table>Proposed diagnostic workup in CCH for differentiation between a panhypopituitarism, a <i>TRH-receptor gene</i> mutation and a <i>TSH<i>β</i>-gene</i> mutation. Rare other conditions mimicking CCH, such as hypothyroxinemia due to prematurity, primary hypothyroidism with delayed TSH elevation, and transient CCH must also be ruled out.   </table>

Case Reports in Pediatrics

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Figure 3

Figure 3: Congenital Central Hypothyroidism due to a Homozygous Mutation in the <i>TSHβ</i> Subunit Gene 

Case Reports in Pediatrics

Congenital Central Hypothyroidism due to a Homozygous Mutation in the TSHβ Subunit Gene

Figure 3