Successful Medical Therapy for Hypophosphatemic Rickets due to Mitochondrial Complex I Deficiency Induced de Toni-Debré-Fanconi Syndrome
Figure 1
Radiographs of knees at diagnosis (a) and before phosphate and calcitriol were commenced. (a) Radiograph of both knees at 1 year of age showed irregularity, fraying and flaring of the distal femoral and proximal tibia metaphyses bilaterally. (b) Radiograph of knees at 3 years of age showed worsening rickets with increased widening, cupping and fraying of metaphyses of the distal femur, the proximal tibia, and fibula. (c) Radiograph of knees at 4 years of age showed persistent widening of metaphyses in both knees.
