Brief Clinical Report: Hypophosphatasia—Diagnostic Considerations and Treatment Outcomes in an Infant

Figure 1

Initial skeletal survey performed at 8 weeks of age demonstrates fraying of the metaphyses of the long bones including the distal tibia (a) and radius and ulna (b). Incidentally note the benign periosteal reaction of the newborn about the tibia. Posttreatment images at 8 months of age (c, d). Only slight cupping of the metaphyses of the tibia (c) and radius and ulna (d) remains.

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