Improvement in Impaired Social Cognition but Not Seizures by Everolimus in a Child with Tuberous Sclerosis-Associated Autism through Increased Serum Antioxidant Proteins and Oxidant/Antioxidant Status

Table 2

Changes of ADI-R, ADOS, ABC, and SRS total scores between baseline and 24 weeks after everolimus treatment.

Variable	Baseline	24 weeks	% decrease
ADI-R total
ADI-R social interaction domain	21	14	33.3
ADI-R communication domain	19	10	47.4
ADI-R restricted/repetitive behavior domain	3	0	100.0
ADOS	16	7	56.2
ABC	50	15	70.0
SRS	107	78	27.2
SCQ	6	3	50.0

ADI-R: Autism Diagnostic Interview-Revised; ADOS: Autism Diagnostic Observation Schedule; ABC: Aberrant Behavior Checklist; SRS: Social Responsiveness Scale; SCQ: Social Communication Questionnaire. % decrease = scores at 24 weeks − the baseline scores/baseline scores × 100.