Case Reports in Pediatrics http://www.hindawi.com The latest articles from Hindawi Publishing Corporation © 2016 , Hindawi Publishing Corporation . All rights reserved. Use of Scrambler Therapy in Acute Paediatric Pain: A Case Report and Review of the Literature Mon, 08 Feb 2016 10:06:31 +0000 http://www.hindawi.com/journals/cripe/2016/2628919/ We report our clinical experience on the effect of Scrambler Therapy (ST) for a child with acute mixed pain refractory to pharmacological treatment. ST, recently proposed as an alternative treatment for chronic neuropathic pain in adults, is a noninvasive approach to relieve pain, by changing pain perception at brain level. It is safe and has no side effects. Further research is needed to assess its efficacy for acute pain and for paediatric population. Sabrina Congedi, Silvia Spadini, Chiara Di Pede, Martina Ometto, Tatiana Franceschi, Valentina De Tommasi, Caterina Agosto, Pierina Lazzarin, and Franca Benini Copyright © 2016 Sabrina Congedi et al. All rights reserved. Colonic Necrosis in a 4-Year-Old with Hyperlipidemic Acute Pancreatitis Wed, 27 Jan 2016 09:45:17 +0000 http://www.hindawi.com/journals/cripe/2016/9123163/ Here we report the case of a 4-year-old male with severe acute pancreatitis due to hyperlipidemia, who presented with abdominal pain, metabolic abnormalities, and colonic necrosis. This colonic complication was secondary to the extension of a large peripancreatic fluid collection causing direct serosal autodigestion by pancreatic enzymes. Two weeks following the initial presentation, the peripancreatic fluid collection developed into a mature pancreatic pseudocyst, which was percutaneously drained. To our knowledge, this is the youngest documented pediatric case of colonic necrosis due to severe pancreatitis and the first descriptive pediatric case of a colonic complication due to hyperlipidemia-induced acute pancreatitis. Tiffany J. Patton, Timothy A. Sentongo, Grace Z. Mak, and Stacy A. Kahn Copyright © 2016 Tiffany J. Patton et al. All rights reserved. A Rare Case of Esophageal Dysphagia in Children: Aberrant Right Subclavian Artery Wed, 20 Jan 2016 16:06:04 +0000 http://www.hindawi.com/journals/cripe/2016/2539374/ Dysphagia is an impairment of swallowing that may involve any structures from the mouth to the stomach. Esophageal dysphagia presents with the sensation of food sticking, pain with swallowing, substernal pressure, or chronic heartburn. There are many causes of esophageal dysphagia, such as motility disorders and mechanical and inflammatory diseases. Infrequently dysphagia arises from extrinsic compression of the esophagus from any vascular anomaly of the aortic arch. The most common embryologic abnormality of the aortic arch is aberrant right subclavian artery, clinically known as arteria lusoria. This abnormality is usually silent. Here, we report a case of six-year-old child presenting to us with a history of progressive dysphagia without respiratory symptoms. A barium esophagogram showed an increase of the physiological esophageal narrowing at the level of aortic arch, while at esophagogastroduodenoscopy there was an extrinsic pulsatile compression of the posterior portion of the esophagus suggesting an extrinsic compression by an aberrant vessel. Angio-CT (computed tomography) scan confirmed the presence of an aberrant right subclavian artery. Claudia Barone, Nicolina Stefania Carucci, and Claudio Romano Copyright © 2016 Claudia Barone et al. All rights reserved. A Case of Polyarteritis Nodosa Associated with Vertebral Artery Vasculitis Treated Successfully with Tocilizumab and Cyclophosphamide Wed, 20 Jan 2016 08:58:45 +0000 http://www.hindawi.com/journals/cripe/2016/7987081/ Pediatric polyarteritis nodosa is rare systemic necrotizing arteritis involving small- and medium-sized muscular arteries characterized by aneurysmal dilatations involving the vessel wall. Aneurysms associated with polyarteritis nodosa are common in visceral arteries; however intracranial aneurysms have also been reported and can be associated with central nervous system symptoms, significant morbidity, and mortality. To our knowledge extracranial involvement of the vertebral arteries has not been reported but has the potential to be deleterious due to fact that they supply the central nervous system vasculature. We present a case of a 3-year-old Haitian boy with polyarteritis nodosa that presented with extracranial vessel involvement of his vertebral arteries. After thorough diagnostic imaging, including a bone scan, ultrasound, Magnetic Resonance Imaging/Angiography, and Computed Tomography Angiography, he was noted to have vertebral artery vasculitis, periostitis, subacute epididymoorchitis, arthritis, and myositis. He met diagnostic criteria for polyarteritis nodosa and was treated with cyclophosphamide, methylprednisolone, and tocilizumab, which resulted in improvement of his inflammatory markers, radiographic findings, and physical symptoms after treatment. To the authors’ knowledge, this is the first report of vertebral artery vasculitis in polyarteritis nodosa as well as successful treatment of the condition using the combination cyclophosphamide and tocilizumab for this condition. Kae Watanabe, Dhanashree A. Rajderkar, and Renee F. Modica Copyright © 2016 Kae Watanabe et al. All rights reserved. Autoimmune Hemolytic Anemia and Hodgkin’s Disease: An Unusual Pediatric Association Tue, 19 Jan 2016 12:35:13 +0000 http://www.hindawi.com/journals/cripe/2016/4598587/ Autoimmune hemolytic anemia (AIHA) is a recognized complication of lymphoproliferative disorders. AIHA associated with Hodgkin’s disease (HD) is uncommon especially in the pediatric population. The diagnosis of AIHA is usually associated with HD at the time of initial presentation or during the course of disease, but it could precede it by years to months. In adults the association of AIHA and HD is more frequent in advanced stages and in the nodular sclerosis and mixed cellularity type HD. Warm immune hemolytic anemia is mainly controlled with steroids and chemotherapy. We report a case of a pediatric patient with direct antiglobulin positive test at the diagnosis of a late relapse of stage III B mixed cellularity type HD. Maria Miguel Gomes, Tereza Oliva, and Armando Pinto Copyright © 2016 Maria Miguel Gomes et al. All rights reserved. Tuberculous Dactylitis: An Uncommon Presentation of a Common Infection Sun, 17 Jan 2016 14:32:06 +0000 http://www.hindawi.com/journals/cripe/2016/4013471/ Tuberculous dactylitis is an unusual form of osteoarticular tuberculosis involving the short tubular bones of hands and feet, which is uncommon beyond six years of age. We report the case of a fifteen-year-old adolescent boy who was diagnosed with tuberculous dactylitis, involving contralateral hand and foot. His diagnosis was delayed due to lack of suspicion of this rare entity. The report also examines the diagnostic difficulties faced by clinicians in arriving at an appropriate diagnosis. G. Nayantara Rao, Jayasri Helen Gali, and S. Narasimha Rao Copyright © 2016 G. Nayantara Rao et al. All rights reserved. Invasive Community-Acquired Methicillin-Resistant Staphylococcus aureus in a Japanese Girl with Disseminating Multiple Organ Infection: A Case Report and Review of Japanese Pediatric Cases Sun, 27 Dec 2015 08:11:38 +0000 http://www.hindawi.com/journals/cripe/2015/291025/ Pediatric invasive community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection is very serious and occasionally fatal. This infectious disease is still a relatively rare and unfamiliar infectious disease in Japan. We report a positive outcome in a 23-month-old Japanese girl with meningitis, osteomyelitis, fasciitis, necrotizing pneumonia, urinary tract infection, and bacteremia due to CA-MRSA treated with linezolid. PCR testing of the CA-MRSA strain was positive for PVL and staphylococcal enterotoxin b and negative for ACME. SCC mec was type IVa. This case underscores the selection of effective combinations of antimicrobial agents for its treatment. We need to be aware of invasive CA-MRSA infection, which rapidly progresses with a serious clinical course, because the incidence of the disease may be increasing in Japan. Ryuta Yonezawa, Tsukasa Kuwana, Kengo Kawamura, and Yasuji Inamo Copyright © 2015 Ryuta Yonezawa et al. All rights reserved. Clinical Phenotype of DiGeorge Syndrome with Negative Genetic Tests: A Case of DiGeorge-Like Syndrome? Thu, 17 Dec 2015 13:50:36 +0000 http://www.hindawi.com/journals/cripe/2015/938074/ We report a case of DiGeorge-like syndrome in which immunodeficiency coexisting with juvenile idiopathic arthritis, congenital heart disease, delay in emergence of language and in motor milestones, feeding and growing problems, enamel hypoplasia, mild skeletal anomalies, and facial dysmorphisms are associated with no abnormalities found on genetic tests. Gianluigi Laccetta, Benedetta Toschi, Antonella Fogli, Veronica Bertini, Angelo Valetto, and Rita Consolini Copyright © 2015 Gianluigi Laccetta et al. All rights reserved. Niemann-Pick Disease Type C Presenting as a Developmental Coordination Disorder with Bullying by Peers in a School-Age Child Wed, 16 Dec 2015 08:21:30 +0000 http://www.hindawi.com/journals/cripe/2015/807591/ Niemann-Pick disease type C (NPC) is a rare progressive neurodegenerative disorder, often with onset after normal early childhood development. Juvenile onset NPC patients slowly develop cerebellar symptoms and cognitive impairment and often experience difficulties at school. However, these problems may be overlooked due to the unpublicized nature of NPC, given that it is a rare metabolic disorder. In this report, we present an 11-year-old male NPC patient, who suffered from clumsiness and difficulties in attention and academic and social skills. His symptoms were initially considered to be due to developmental coordination disorder (DCD) coexisting with bullying by peers. DCD is a type of neurodevelopmental disorder defined according to DSM-IV and is characterized by clumsiness that interferes with academic achievement and social integration not due to other general medical conditions. However, a detailed investigation of the patient suggested that the problems could be attributed to the onset of NPC. Clinicians should keep neurodegenerative disorders as differential diagnosis of children with multiple school problems. Ryo Suzuki, Atsushi Tanaka, Toshiharu Matsui, Tetsuki Gunji, Jun Tohyama, Aya Nairita, Eiji Nanba, and Kousaku Ohno Copyright © 2015 Ryo Suzuki et al. All rights reserved. Bladder Wall Telangiectasia in a Patient with Ataxia-Telangiectasia and How to Manage? Sun, 29 Nov 2015 14:00:53 +0000 http://www.hindawi.com/journals/cripe/2015/615368/ Ataxia-telangiectasia (A-T) is a rare neurodegenerative, inherited disease causing severe morbidity. Oculocutaneous telangiectasias are almost constant findings among the affected cases as telangiectasia is considered the main clinical finding for diagnosis. Vascular abnormalities in organs have been reported infrequently but bladder wall telangiectasias are extremely rare. We aimed to report recurrent hemorrhage from bladder wall telangiectasia in a 9-year-old boy with A-T who had received intravenous cyclophosphamide for non-Hodgkin’s lymphoma. Since A-T patients are known to be more susceptible to chemical agents, we suggested that possibly cyclophosphamide was the drug which induced bladder wall injury in this patient. Fatma Deniz Aygün, Serdar Nepesov, Haluk Çokuğraş, and Yıldız Camcıoğlu Copyright © 2015 Fatma Deniz Aygün et al. All rights reserved. Cystic Fibrosis in a Female Infant with Cardiac, Ocular, and Musculoskeletal Anomalies Sun, 29 Nov 2015 13:07:38 +0000 http://www.hindawi.com/journals/cripe/2015/379018/ Cystic fibrosis (CF) remains the most common hereditary disease in the western population. Its concomitant presence with other congenital abnormalities is a rare phenomenon with very little documentation. In this case report we describe a case of cystic fibrosis in a female infant with cardiac, ocular, and musculoskeletal abnormalities. A brief literature review is also provided. Azhar Farooqui, Susan Gamal Eldin, Muna Dawood Ali, Ali AlTalhi, and Ahmad AlDigheari Copyright © 2015 Azhar Farooqui et al. All rights reserved. Goldenhar Syndrome Associated with Extensive Arterial Malformations Wed, 25 Nov 2015 08:44:37 +0000 http://www.hindawi.com/journals/cripe/2015/954628/ Goldenhar Syndrome is characterized by craniofacial, ocular and vertebral defects secondary to abnormal development of the 1st and 2nd branchial arches and vertebrae. Other findings include cardiac and vascular abnormalities. Though these associations are known, the specific anomalies are not well defined. We present a 7-month-old infant with intermittent respiratory distress that did not improve with respiratory interventions. Echocardiogram suggested a double aortic arch. Cardiac CT angiogram confirmed a right arch and aberrant, stenotic left subclavian artery, dilation of the main pulmonary artery, and agenesis of the left thyroid lobe. Repeat echocardiograms were concerning for severely dilated coronary arteries. Given dilation, a rheumatologic workup ensued, only identifying few weakly positive autoantibodies. Further imaging demonstrated narrowing of the aorta below the renal arteries and extending into the common iliac arteries and proximal femoral arteries. Given a physical exam devoid of rheumatologic findings, only weakly positive autoantibodies, normal inflammatory markers, and presence of the coronary artery dilation, the peripheral artery narrowings were not thought to be vasculitic. This case illustrates the need to identify definitive anomalies related to Goldenhar Syndrome. Although this infant’s presentation is rare, recognition of specific vascular findings will help differentiate Goldenhar Syndrome from other disease processes. Renee Frances Modica, L. Daphna Yasova Barbeau, Jennifer Co-Vu, Richard D. Beegle, and Charles A. Williams Copyright © 2015 Renee Frances Modica et al. All rights reserved. A Case of Hemolytic Disease of the Newborn due to Dia Antibody Sun, 22 Nov 2015 07:28:01 +0000 http://www.hindawi.com/journals/cripe/2015/897803/ Anti- is a clinically significant red cell antibody known to cause hemolytic disease of the newborn. Here, we report on a case of mild hemolytic disease of the newborn caused by antibody. The mother had three prior pregnancies with no history of blood transfusion. She delivered a preterm 35-week-old female newborn by cesarean section. The neonate developed anemia and mild icterus on postnatal day five with hemoglobin of 9500 mg/dL and total bilirubin of 10 mg/dL. The direct antiglobulin test on the neonate’s red blood cells was positive. The maternal serum and an eluate from the infant RBCs were negative in routine antibody detection tests but were positive using commercially prepared Di(a+) red cells. The neonate was discharged home in stable condition following treatment with erythropoietin and phototherapy. When a newborn has a positive DAT in the absence of major blood group incompatibility or commonly detected RBC antibodies, an antibody to a low frequency antigen such as must be considered. Further immunohematology tests are required to determine presence of the antibody and the clinician must be alerted to closely monitor the infant for signs of anemia and hemolysis. Ashif Jethava, Esperanza Olivares, and Sherry Shariatmadar Copyright © 2015 Ashif Jethava et al. All rights reserved. Abdominal Lymphonodular Cryptococcosis in an Immunocompetent Child Mon, 16 Nov 2015 13:36:31 +0000 http://www.hindawi.com/journals/cripe/2015/347403/ We describe our experience with an apparently immunocompetent child presenting with pyrexia of unknown origin without focal signs. Investigations revealed lymphadenopathy at lung hila, mesentery, and porta hepatis. The child had received at least two months of empiric antituberculous therapy (ATT) before she came to us. A CT-guided biopsy revealed granulomatous inflammation. PAS stain showed yeasts which stained blue with Alcian blue, suggesting C. neoformans. Mehjabeen Zaidi, Sonia Qureshi, Sadia Shakoor, Saira Fatima, and Fatima Mir Copyright © 2015 Mehjabeen Zaidi et al. All rights reserved. A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture Thu, 12 Nov 2015 07:06:43 +0000 http://www.hindawi.com/journals/cripe/2015/538762/ Idiopathic Hypereosinophilic Syndrome (IHES) is a rare disease that can be difficult to diagnose as the differential is broad. This disease can cause significant morbidity and mortality if left untreated. Our patient is a 17-year-old adolescent female who presented with nonspecific symptoms of abdominal pain and malaise. She was incidentally found to have hypereosinophilia of 16,000 on complete blood count and nonspecific colitis and pulmonary edema on computed tomography. She went into cardiogenic shock due to papillary rupture of her mitral valve requiring extreme life support measures including intubation and extracorporal membrane oxygenation (ECMO) as well as mitral valve replacement. Pathology of the valve showed eosinophilic infiltration as the underlying etiology. The patient was diagnosed with IHES after the exclusion of infectious, rheumatologic, and oncologic causes. She was treated with steroids with improvement of her symptoms and scheduled for close follow-up. In general patients with IHES that have cardiac involvement have poorer prognoses. Tiffany Tamse, Avind Rampersad, Alejandro Jordan-Villegas, and Jill Ireland Copyright © 2015 Tiffany Tamse et al. All rights reserved. Eikenella corrodens Sepsis with Cerebrospinal Fluid Pleocytosis in a Very Low Birth Weight Neonate Mon, 09 Nov 2015 08:32:28 +0000 http://www.hindawi.com/journals/cripe/2015/686812/ We report a case of Eikenella corrodens sepsis associated with CSF pleocytosis in a very low birth weight neonate. A 1000-gram male neonate was born at 27-week gestation due to preterm labor. The patient presented with signs and symptoms of sepsis and was treated for suspected meningitis with intravenous ampicillin and gentamicin for 7 days, with cefotaxime added for three weeks. He had a normal brain MRI at discharge and normal development at 6 months of life. To our knowledge, this is the first case of E. corrodens sepsis and associated meningitis in a very low birth weight neonate. Christopher Sawyer, Dimitrios Angelis, and Robert Bennett Copyright © 2015 Christopher Sawyer et al. All rights reserved. Acute Lymphocytic Leukemia with Bilateral Renal Masses Masquerading as Nephroblastomatosis Tue, 03 Nov 2015 06:38:50 +0000 http://www.hindawi.com/journals/cripe/2015/806494/ Acute lymphoblastic leukemia (ALL) is the most common malignancy in the pediatric patient population. However, renal involvement as the primary manifestation of ALL is rare. We report a case of a 4-year-old boy with bilateral renal lesions resembling nephroblastic rests as the first finding of early stage ALL preceding hematological changes and subsequent classic clinical findings by two weeks. These renal hypodensities completely resolved after one week of induction chemotherapy. This case demonstrates that renal involvement can be the only initial presenting finding of leukemia. Children with lesions resembling nephroblastic rests need appropriate surveillance due to the risk of malignant disease. Poonam Thakore, Salim Aljabari, Curtis Turner, and Tetyana L. Vasylyeva Copyright © 2015 Poonam Thakore et al. All rights reserved. Klippel-Trenaunay Syndrome with Extensive Lymphangiomas Mon, 26 Oct 2015 08:30:49 +0000 http://www.hindawi.com/journals/cripe/2015/581394/ Klippel-Trenaunay syndrome (KTS) is a rare disorder characterized by the triad of vascular malformations, venous varicosities, and bone and soft-tissue hypertrophy. We present a case of Klippel-Trenaunay syndrome with limb hypertrophy, port-wine stains, lymphangiomas, and venous varicosities in the limbs. Sirin Mneimneh, Ali Tabaja, and Mariam Rajab Copyright © 2015 Sirin Mneimneh et al. All rights reserved. Update Review and Clinical Presentation in Congenital Insensitivity to Pain and Anhidrosis Thu, 22 Oct 2015 12:02:38 +0000 http://www.hindawi.com/journals/cripe/2015/589852/ Introduction. Congenital insensitivity to pain and anhidrosis (CIPA) or hereditary sensory and autonomic neuropathy type IV is an extremely rare syndrome. Three clinical findings define the syndrome: insensitivity to pain, impossibility to sweat, and mental retardation. This pathology is caused by a genetic mutation in the NTRK1 gene, which encodes a tyrosine receptor (TrkA) for nerve growth factor (NGF). Methods. The consultation of a child female in our center with CIPA and a tibia fracture in pseudoarthrosis encouraged us to carefully review literature and examine the therapeutic possibilities. A thorough review of literature published in Pubmed was done about CIPA and other connected medical issues mentioned in the paper. Conclusions. The therapeutic approach of CIPA remains unclear. The preventive approach remains the only possible treatment of CIPA. We propose two new important concepts in the therapeutic approach for these patients: (1) early surgical treatment for long bone fractures to prevent pseudoarthrosis and to allow early weight bearing, decreasing the risk of further osteopenia, and (2) bisphosphonates to avoid the progression of osteopenia and to reduce the number of consecutive fractures. L. M. Pérez-López, M. Cabrera-González, D. Gutiérrez-de la Iglesia, S. Ricart, and G. Knörr-Giménez Copyright © 2015 L. M. Pérez-López et al. All rights reserved. Neonatal Hyperglycemia due to Transient Neonatal Diabetes Mellitus in Puerto Rico Tue, 20 Oct 2015 06:41:42 +0000 http://www.hindawi.com/journals/cripe/2015/984214/ Neonatal hyperglycemia is a metabolic disorder found in the neonatal intensive care units. Neonatal diabetes mellitus (NDM) is a very uncommon cause of hyperglycemia in the newborn, occurring in 1 in every 400,000 births. There are two subtypes of neonatal diabetes mellitus: permanent neonatal diabetes mellitus (PNDM) and transient neonatal diabetes mellitus (TNDM). We describe a term, small for gestational age, female neonate with transient neonatal diabetes mellitus who presented with poor feeding tolerance and vomiting associated with hyperglycemia (385 mg/dL), glycosuria, and metabolic acidosis within the first 12 hours of life. The neonate was treated with intravenous insulin, obtaining a slight control of hyperglycemia. An adequate glycemia was achieved at 5 weeks of life. The molecular studies showed complete loss of maternal methylation at the TND differentially methylated region on chromosome 6q24. The etiology of this neonate’s hyperglycemia was a hypomethylation of the maternal TND locus. A rare cause of neonatal diabetes mellitus must be considered if a neonate presents refractory hyperglycemia. To our knowledge, this is the first case reported in Puerto Rico of transient neonatal mellitus due to the uncommon mechanism of maternal hypomethylation of the TND locus. Its prevalence in Puerto Rico is unknown. N. Fargas-Berríos, L. García-Fragoso, I. García-García, and M. Valcárcel Copyright © 2015 N. Fargas-Berríos et al. All rights reserved. Corrigendum to “Two Mutations in Surfactant Protein C Gene Associated with Neonatal Respiratory Distress” Mon, 19 Oct 2015 11:22:13 +0000 http://www.hindawi.com/journals/cripe/2015/592053/ Anna Tarocco, Elisa Ballardini, Maria Raffaella Contiero, Giampaolo Garani, and Silvia Fanaro Copyright © 2015 Anna Tarocco et al. All rights reserved. Postdural Puncture Superior Sagittal Sinus Thrombosis in a Juvenile Case of Clinically Isolated Syndrome Mon, 19 Oct 2015 09:53:39 +0000 http://www.hindawi.com/journals/cripe/2015/358164/ Background. The causes of cerebral venous thrombosis (CVT) are manifold as is its clinical presentation. Case. We report the case of a CVT following lumbar puncture and intravenous glucocorticosteroid therapy in a female adolescent with a clinically isolated syndrome and risk factors for thrombosis. Conclusion. In adolescent patients with acute inflammatory disease undergoing lumbar puncture followed by intravenous high-dose glucocorticosteroid therapy, one should be aware of the elevated risk for thrombosis. A persistent headache with change in the headache pattern and loss of a postural component might be a sign for CVT, requiring emergency imaging of the brain. Miriam Michel, Edda Haberlandt, Matthias Baumann, Andreas Entenmann, Michaela Wagner, and Kevin Rostasy Copyright © 2015 Miriam Michel et al. All rights reserved. Corrigendum to “Netherton Syndrome in a Neonate with Possible Growth Hormone Deficiency and Transient Hyperaldosteronism” Tue, 13 Oct 2015 08:38:19 +0000 http://www.hindawi.com/journals/cripe/2015/328717/ Ilias Chatziioannidis, Evgenia Babatseva, Aikaterini Patsatsi, Asimina Galli-Tsinopoulou, Constantina Sarri, Maria Lithoxopoulou, George Mitsiakos, Paraskevi Karagianni, Christos Tsakalidis, Zissis Mamuris, and Nikolaos Nikolaidis Copyright © 2015 Ilias Chatziioannidis et al. All rights reserved. Subcutaneous Fat Necrosis of the Newborn: A Case Report of a Term Infant Presenting with Malaise and Fever at Age of 9 Weeks Thu, 08 Oct 2015 09:46:26 +0000 http://www.hindawi.com/journals/cripe/2015/638962/ Background. Subcutaneous fat necrosis (SFN) is a rare, temporary, self-limited pathology affecting adipose tissue of full-term or postmature neonates. It is a rare entity especially in Nigeria and usually occurs in the first weeks following a complicated delivery. Because it is not very common, diagnosis is easily missed. It may resolve spontaneously without sequelae but patients need to be followed up because of development of late complications especially hypercalcemia. We report a case of SFN of the newborn noted within one week of birth and highlight the need for proper prompt diagnosis and the need for follow-up to assess possible complications. Ayuk Adaeze Chikaodinaka and Anikene Chukwuemeka Jude Copyright © 2015 Ayuk Adaeze Chikaodinaka and Anikene Chukwuemeka Jude. All rights reserved. A Case Study of Intractable Vomiting with Final Diagnosis of Neuromyelitis Optica Mon, 05 Oct 2015 09:46:52 +0000 http://www.hindawi.com/journals/cripe/2015/291390/ This case study presents a patient living in a suburban/rural community who received appropriate referral to secondary and tertiary care for nausea and vomiting, accompanied by waxing and waning neurological symptoms, yet proved difficult to diagnose. This patient is presented to draw attention to a rare neurological disorder which should be included in the differential diagnosis of nausea and vomiting with some key neurological complaints, even in the absence of physical findings. Rachel Bramson and Angela Hairrell Copyright © 2015 Rachel Bramson and Angela Hairrell. All rights reserved. Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging Tue, 08 Sep 2015 15:34:50 +0000 http://www.hindawi.com/journals/cripe/2015/537530/ Kasabach-Merritt phenomenon (KMP) is characterized by vascular tumour and consumptive coagulopathy with life-threatening thrombocytopenia, prolonged prothrombin time and partial thromboplastin time, hypofibrinogenemia, and the presence of high fibrin split products. We report a case of 3-year-old boy with local aggressive vascular lesions associated with KMP. Magnetic resonance imaging revealed an extensive lesion at paravertebral and retroperitoneal regions that was infiltrating vertebrae. Although we did not get any response to steroid or propranolol treatment, partial response was observed radiologically with interferon-alpha treatment. Unfortunately, the patient died because of the uncontrolled consumptive coagulopathy that led to intracranial hemorrhage which was caused by huge knee hematoma after minor trauma. Gonca Keskindemirci, Deniz Tuğcu, Gönül Aydoğan, Arzu Akçay, Nuray Aktay Ayaz, Ali Er, Ensar Yekeler, and Bilge Bilgiç Copyright © 2015 Gonca Keskindemirci et al. All rights reserved. Cardiac Tamponade Associated with the Presentation of Anaplastic Large Cell Lymphoma in a 2-Year-Old Child Tue, 08 Sep 2015 07:49:48 +0000 http://www.hindawi.com/journals/cripe/2015/487491/ The anaplastic large cell lymphoma is a rare entity in pediatric patients. We present an unusual case of pericardial involvement, quite uncommon as extranodal presentation of this type of disorder, that provoked a life-risk situation requiring an urgent pericardiocentesis. To our knowledge, this is the first report on a child with pericardial involvement without an associated cardiac mass secondary to anaplastic large cell lymphoma in pediatric age. We report the case of a 21-month-old Caucasian male infant with cardiac tamponade associated with the presentation of anaplastic large cell lymphoma. Initially, the child presented with 24-day prolonged fever syndrome, cutaneous lesions associated with hepatomegaly, inguinal adenopathies, and pneumonia. After a 21-day asymptomatic period, polypnea and tachycardia were detected in a clinical check-up. Chest X-ray revealed a remarkable increase of the cardiothoracic index. The anaplastic large cell lymphoma has a high incidence of extranodal involvement but myocardial or pericardial involvements are rare. For this reason, we recommend a close monitoring of patients with a differential diagnosis of anaplastic large cell lymphoma. Gema Mira-Perceval Juan, Pedro J. Alcalá Minagorre, Ana M. Huertas Sánchez, Sheila Segura Sánchez, Silvia López Iniesta, Francisco J. De León Marrero, Estela Costa Navarro, and María Niveiro de Jaime Copyright © 2015 Gema Mira-Perceval Juan et al. All rights reserved. A Case of Delayed Interval Delivery with a Successful Hospital Move Sun, 30 Aug 2015 12:53:58 +0000 http://www.hindawi.com/journals/cripe/2015/802097/ This report is the first case of delayed interval twin delivery in which the first infant and mother survived without major morbidity following transport to another facility. In addition, this case is only the second report of asynchronous delivery in which both twins survived and neither suffered any major morbidity. A 30-year-old G5P1031 African American female with a diamniotic/dichorionic twin pregnancy presented to U.S. Naval Hospital Okinawa, Japan, at 22 + 5 weeks due to vaginal bleeding. At 23 + 2 weeks, Twin A was born secondary to advanced cervical dilation. Twin A’s birth weight was 650 g with APGAR scores of 6 (1 min) and 7 (5 min). Following delivery of Twin A, Placenta A was left in utero with high ligation of the umbilical cord. Due to a scheduled hospital move, the mother and Twin A were transported to the new facility at Camp Foster. Three weeks later, Twin B was delivered at 26 + 4 weeks. Twin B’s birth weight was 930 g with APGAR scores of 3 (1 min) and 7 (5 min). Both twins were discharged without IVH, PVL, ROP, or CLD. This case demonstrates the possibility of transporting both the mother and surviving infant A to a higher level of care prior to delivery of subsequent fetuses. Toshifumi Yodoshi, Elizabeth Tipton, and Christopher A. Rouse Copyright © 2015 Toshifumi Yodoshi et al. All rights reserved. A Rare Cause of Prepubertal Gynecomastia: Sertoli Cell Tumor Sun, 23 Aug 2015 13:41:57 +0000 http://www.hindawi.com/journals/cripe/2015/439239/ Prepubertal gynecomastia due to testis tumors is a very rare condition. Nearly 5% of the patients with testicular mass present with gynecomastia. Sertoli cell tumors are sporadic in 60% of the reported cases, while the remaining is a component of multiple neoplasia syndromes such as Peutz-Jeghers syndrome and Carney complex. We present a 4-year-old boy with gynecomastia due to Sertoli cell tumor with no evidence of Peutz-Jeghers syndrome or Carney complex. Fatma Dursun, Şeyma Meliha Su Dur, Ceyhan Şahin, Heves Kırmızıbekmez, Murat Hakan Karabulut, and Asım Yörük Copyright © 2015 Fatma Dursun et al. All rights reserved. Inguinal Hernia Containing Uterus, Fallopian Tube, and Ovary in a Premature Newborn Sun, 16 Aug 2015 13:31:19 +0000 http://www.hindawi.com/journals/cripe/2015/807309/ A female infant weighing 2,200 g was delivered at 34 weeks of gestation by vaginal delivery. She presented with an irreducible mass in the left inguinal region at 32 days of age. An ultrasonography (US) was performed and an incarcerated hernia containing uterus, fallopian tube, and ovary was diagnosed preoperatively. Surgery was performed through an inguinal approach; the uterus, fallopian tube, and ovary were found in the hernia sac. High ligation and an additional repair of the internal inguinal ring were performed. Patent processus vaginalis was found during contralateral exploration and also closed. The postoperative course was uneventful. After one year of follow-up, there have been no signs of recurrence. Kıvılcım Karadeniz Cerit, Rabia Ergelen, Emel Colak, and Tolga E. Dagli Copyright © 2015 Kıvılcım Karadeniz Cerit et al. All rights reserved.