Case Reports in Pediatrics http://www.hindawi.com The latest articles from Hindawi Publishing Corporation © 2016 , Hindawi Publishing Corporation . All rights reserved. Corrigendum to “Multiple Congenital Colonic Stenosis: A Rare Gastrointestinal Malformation” Mon, 25 Jul 2016 12:38:17 +0000 http://www.hindawi.com/journals/cripe/2016/5353012/ Elisa Zambaiti, Cinzia Chiaramonte, Sergio Salerno, Giuseppe Li Voti, and Fortunato Siracusa Copyright © 2016 Elisa Zambaiti et al. All rights reserved. An Uncommon Case of Adolescent Ovarian Teratoma Incarcerated in Inguinal Hernia Wed, 20 Jul 2016 09:51:19 +0000 http://www.hindawi.com/journals/cripe/2016/4534053/ Mature cystic teratoma is the most frequent benign ovarian neoplastic lesion in adolescents and is generally composed of fully differentiated tissue arising from multipotential three germinal layers. It accounts for approximately 50% of benign ovarian tumors in childhood. Rarely, a bilateral, synchronous, or metachronous presentation can be observed, supporting a conservative approach as the first surgical approach. We report a case of an ovarian mature cystic incarcerated in indirect inguinal hernia in a 15-year-old girl undergoing ovary-sparing surgery. To our knowledge this is the first case of such lesion incarcerated in an inguinal hernia reported in literature. Marco Pensabene, Vincenza Girgenti, Marcello Cimador, Giuseppe Li Voti, Vito Rodolico, and Fortunato Siracusa Copyright © 2016 Marco Pensabene et al. All rights reserved. Persistence of Retinopathy of Prematurity in an Infant with Tetralogy of Fallot Wed, 20 Jul 2016 05:59:31 +0000 http://www.hindawi.com/journals/cripe/2016/7070316/ We report an infant with tetralogy of fallot (TOF) who was born at 35 weeks of gestation and of 1700 g birth weight and presented with persistent retinopathy of prematurity (ROP) at 6 months of age. Follow-up ophthalmic examinations were done at 2, 3, and 4 weeks of age. A demarcation line in Zone II was noticed on the first ocular examination done at 4 weeks of postnatal age. At 6 months of postnatal age, the infant still had an avascular peripheral retina with the demarcation line in Zone II. Even though this index subject did not have any typical risk factors for ROP, TOF seems to be the probable reason for developing as well as persistence of avascular retina. Murat Gunay, Taner Yavuz, Gokhan Celik, and Gunay Uludag Copyright © 2016 Murat Gunay et al. All rights reserved. Vitamin D and Risk for Vitamin A Intoxication in an 18-Month-Old Boy Sun, 10 Jul 2016 12:39:15 +0000 http://www.hindawi.com/journals/cripe/2016/1395718/ An 18-month-old boy presented with abdominal pain, vomiting, diarrhea, and poor appetite for 6 days. He had been given a multivitamin preparation once daily, containing 50.000 IU of vitamin D and 10.000 IU of vitamin A for a wide anterior fontanelle for about three months. He presented with hypercalcemia, low levels of parathyroid hormone (PTH), and very high serum 25-hydroxyvitamin D (25-OHD) levels. Renal ultrasound showed nephrocalcinosis. He did not have sign or symptom of vitamin A intoxication. Patient was successfully treated with intravenous hydration, furosemide, and prednisolone. With treatment, serum calcium returned rapidly to the normal range and serum 25-OHD levels were reduced progressively. In conclusion the diagnosis of vitamin D deficiency rickets without checking 25-OHD levels may cause redundant treatment that leads to vitamin D intoxication (VDI). Valentina Talarico, Massimo Barreca, Rossella Galiano, Maria Concetta Galati, and Giuseppe Raiola Copyright © 2016 Valentina Talarico et al. All rights reserved. A Physician’s Nightmare: Fever of Unknown Origin Tue, 28 Jun 2016 10:31:28 +0000 http://www.hindawi.com/journals/cripe/2016/5437971/ Fever of unknown origin (FUO) remains to be a challenge despite advancement in diagnostic technologies and procedures. FUO is considered when fever presents intermittently without an explanation. It has been linked to various etiologies, which makes it difficult to diagnose. We present the case of 18-month-old female with recurrent fever, splenomegaly, abdominal pain, and constipation. The workup for her symptoms revealed wandering spleen. Wandering spleen is a result from excessive laxity or absence of splenic ligaments. The patient underwent splenectomy and was advised to continue on Senna, Miralax, and high fiber diet. Her mother reported that the fever is no longer present and there is marked improvement in her constipation and abdominal pain after splenectomy. Sana Din, Farrukh Anwer, and Mirza Beg Copyright © 2016 Sana Din et al. All rights reserved. Regression of Cardiac Rhabdomyomas in a Neonate after Everolimus Treatment Mon, 27 Jun 2016 06:49:35 +0000 http://www.hindawi.com/journals/cripe/2016/8712962/ Cardiac rhabdomyoma often shows spontaneous regression and usually requires only close follow-up. However, patients with symptomatic inoperable rhabdomyomas may be candidates for everolimus treatment. Our patient had multiple inoperable cardiac rhabdomyomas causing serious left ventricle outflow-tract obstruction that showed a dramatic reduction in the size after everolimus therapy, a mammalian target of rapamycin (mTOR) inhibitor. After discontinuation of therapy, an increase in the diameter of masses occurred and everolimus was restarted. After 6 months of treatment, rhabdomyomas decreased in size and therapy was stopped. In conclusion, everolimus could be a possible novel therapy for neonates with clinically significant rhabdomyomas. Helen Bornaun, Kazım Öztarhan, Tugba Erener-Ercan, Reyhan Dedeoğlu, Deniz Tugcu, Çiğdem Aydoğmuş, Merih Cetinkaya, and Sultan Kavuncuoglu Copyright © 2016 Helen Bornaun et al. All rights reserved. Unusual Ventilatory Response to Exercise in Patient with Arnold-Chiari Type 1 Malformation after Posterior Fossa Decompression Tue, 21 Jun 2016 13:46:03 +0000 http://www.hindawi.com/journals/cripe/2016/8359838/ We present a case of a 17-year-old Hispanic male with Arnold-Chiari Type 1 [AC-Type 1] with syringomyelia, status post decompression, who complains of exercise intolerance, headaches, and fatigue with exertion. The patient was found to have diurnal hypercapnia and nocturnal alveolar hypoventilation. Cardiopulmonary testing revealed blunting of the ventilatory response to the rise in carbon dioxide (CO2) resulting in failure of the parallel correlation between increased CO2 levels and ventilation; the expected vertical relationship between PETCO2 and minute ventilation during exercise was replaced with an almost horizontal relationship. No new pathology of the brainstem was discovered by MRI or neurological evaluation to explain this phenomenon. The patient was placed on continuous noninvasive open ventilation (NIOV) during the day and CPAP at night for a period of 6 months. His pCO2 level decreased to normal limits and his symptoms improved; specifically, he experienced less headaches and fatigue during exercise. In this report, we describe the abnormal response to exercise that patients with AC-Type 1 could potentially experience, even after decompression, characterized by the impairment of ventilator response to hypercapnia during exertion, reflecting a complete loss of chemical influence on breathing with no evidence of abnormality in the corticospinal pathway. Keely Smith, Ana M. Gomez-Rubio, Tomika S. Harris, Lauren E. Brooks, and Ricardo A. Mosquera Copyright © 2016 Keely Smith et al. All rights reserved. Cooccurrence of Postural Orthostatic Tachycardia Syndrome with Two Different Clinical Entities Sun, 19 Jun 2016 12:17:27 +0000 http://www.hindawi.com/journals/cripe/2016/8542158/ Postural orthostatic tachycardia syndrome (POTS) is an abnormal heart rate response to a positional change. Several potential mechanisms for pathophysiology of POTS are defined. This syndrome can coexist with different clinical situations. In our report, the first case was a 13-year-old female who has been followed up for diagnosis of homocystinuria. She was admitted to our outpatient clinic with complaints of dizziness after suddenly moving from supine to upright position and chest pain after exercise. Tilt table test was performed to evaluate dizziness. According to the tilt table test the patient was diagnosed with POTS. The second case was a 17-year-old female who had been evaluated in different centers with the complaints of fainting, bruising, redness, and swelling on the hands and feet after moving from supine position to upright position during the last 4 years. Postural orthostatic tachycardia syndrome was diagnosed by tilt table test and ivabradine was started. Herein, we aimed to point out the cooccurrence of different clinical entities and POTS. Funda Oztunc, Sezen Ugan Atik, Reyhan Dedeoglu, Firuze Erbek Alp, and Selman Gokalp Copyright © 2016 Funda Oztunc et al. All rights reserved. Ibuprofen for Ductus Arteriosus Months after Birth Tue, 14 Jun 2016 09:10:45 +0000 http://www.hindawi.com/journals/cripe/2016/2659389/ Ibuprofen is a well-known agent used to treat patent ductus arteriosus in preterm neonates in the first days of life. In the current case report we illustrate the potential use of ibuprofen in two preterm neonates 60 and 88 days after birth, respectively. To our knowledge, this is the first report on the effects of ibuprofen on patent ductus arteriosus in preterm newborns after months of life. These cases suggest that the ductus arteriosus does not become refractory for ibuprofen after the first days of life. Late closure of the duct with ibuprofen might still improve the cardiorespiratory condition and prevent infants from surgical closure. Controlled trials are necessary to further study these findings. Odile Frauenfelder, Ingrid M. van Beynum, Irwin K. M. Reiss, and Sinno H. P. Simons Copyright © 2016 Odile Frauenfelder et al. All rights reserved. Diplopia, Convergent Strabismus, and Eye Abduction Palsy in a 12-Year-Old Boy with Autoimmune Thyroiditis Thu, 09 Jun 2016 12:01:35 +0000 http://www.hindawi.com/journals/cripe/2016/5823137/ Pseudotumor cerebri (PTC) is defined by clinical criteria of increased intracranial pressure, elevated intracranial pressure with normal cerebrospinal fluid (CSF) composition, and exclusion of other causes such tumors, vascular abnormalities, or infections. The association of PTC with levothyroxine (LT4) has been reported. A 12-year-old boy has been followed up for autoimmune thyroiditis under LT4. Family history was irrelevant for endocrine or autoimmune diseases. A TSH level of 4.43 μUI/mL (0.39–3.10) motivated a LT4 adjustment from 75 to 88 μg/day. Five weeks later, he developed horizontal diplopia, convergent strabismus with left eye abduction palsy, and papilledema. Laboratorial evaluation revealed elevated free thyroxine level (1.05 ng/dL [0.65–1.01]) and low TSH, without other alterations. Lumbar puncture was performed and CSF opening pressure was 24 cm H2O with normal composition. Blood and CSF cultures were sterile. Brain MRI was normal. LT4 was temporarily discontinued and progressive improvement was observed, with a normal fundoscopy at day 10 and reversion of diplopia one month later. LT4 was restarted at lower dose and gradually titrated. The boy is currently asymptomatic. This case discloses the potential role of LT4 in inducing PTC. Despite its rarity and unclear association, PTC must be seen as a potential complication of LT4, after excluding all other intracranial hypertension causes. Pedro Marques, Sandra Jacinto, Maria do Carmo Pinto, Catarina Limbert, and Lurdes Lopes Copyright © 2016 Pedro Marques et al. All rights reserved. Acute Hepatitis and Pancytopenia in Healthy Infant with Adenovirus Wed, 01 Jun 2016 13:16:48 +0000 http://www.hindawi.com/journals/cripe/2016/8648190/ Adenoviruses are a common cause of respiratory infection, pharyngitis, and conjunctivitis in infants and young children. They are known to cause hepatitis and liver failure in immunocompromised patients; they are a rare cause of hepatitis in immunocompetent patients and have been known to cause fulminant hepatic failure. We present a 23-month-old immunocompetent infant who presented with acute noncholestatic hepatitis, hypoalbuminemia, generalized anasarca, and pancytopenia secondary to adenovirus infection. Amr Matoq and Asma Salahuddin Copyright © 2016 Amr Matoq and Asma Salahuddin. All rights reserved. Ischemic Stroke in Confederation with Trivial Head Trauma Sun, 29 May 2016 14:15:03 +0000 http://www.hindawi.com/journals/cripe/2016/2572958/ Minor head injuries in children are common, resulting in brain concussion, and these injuries mostly end up without complications. Usually head trauma results in hemorrhagic stroke. Here we present a case of ischemic stroke following a trivial head trauma. A 10-month-old girl presented with posttraumatic right sided hemiparesis with right sided facial palsy. MRI brain revealed an area of acute infarct in the left capsuloganglionic region. The child was initially managed conservatively, as the hematological parameters were normal, and was started on anticoagulant therapy. An improvement in the clinical condition was achieved in 12 hrs of treatment with gain in power and resolution of weakness in 10 days. The specific cause for hemiparesis in the child is not elicited; possibility of genetic and environmental factors can be attributable. Archana Balachandran, Siddarameshwar Kalyanshettar, Shankargouda Patil, and Vijaykumar Shegji Copyright © 2016 Archana Balachandran et al. All rights reserved. Follicular Bronchiolitis in a Nigerian Female Child: A Case Report and Review of the Literature Thu, 26 May 2016 14:15:33 +0000 http://www.hindawi.com/journals/cripe/2016/1096953/ Small airways diseases are not uncommon in childhood. They account for about 28.4% of hospital admissions for lower respiratory tract infections in South West Nigeria, most of which are due to respiratory syncytial virus (RSV) infection. Noninfectious causes of small airways diseases, on the other hand, are poorly recognized and rarely feature in the differential diagnoses of chronic/recurrent lower respiratory tract disease in our environment. We present a case of follicular bronchiolitis in a 2.5-year-old Nigerian female who had left upper lobectomy on account of recurrent cough and progressive shortness of breath. Nzechukwu Zimudo Ikeri, Godwin O. Umerah, Christopher Emeka Ugwu, Olugbenga Olusoji, Adekunle Adeyomoye, Ekanem Ekure, and Adetola Olubunmi Daramola Copyright © 2016 Nzechukwu Zimudo Ikeri et al. All rights reserved. Cloacal Exstrophy Repair with Primary Closure of Bladder Exstrophy: A Case Report and Review of Literature Mon, 23 May 2016 12:30:05 +0000 http://www.hindawi.com/journals/cripe/2016/8538935/ Cloacal exstrophy is the most complex congenital, ventral, abdominal wall defect. Traditionally surgery consists of a staged approach to repair which takes place on many separate theatre visits. In this case a primary approach was undertaken resulting in a relatively short inpatient stay and a reduced risk from multiple surgical procedures under general anaesthesia. George Bethell, Navroop Johal, and Peter Cuckow Copyright © 2016 George Bethell et al. All rights reserved. A Case of Apparent Life-Threatening Event: Comorbid Gastric Volvulus Associated Gastroesophageal Reflux Disease and Epilepsy in a 4-Month-Old Boy Thu, 12 May 2016 08:14:09 +0000 http://www.hindawi.com/journals/cripe/2016/5717246/ Most isolated episodes of apparent life-threatening events (ALTEs) do not lead to the diagnosis of serious conditions, and their prognoses are generally benign. However, recurrent ALTEs are often associated with a risk of future serious adverse events and should be evaluated for appropriate management. Here we present ALTE case in which gastric volvulus associated gastroesophageal reflux disease was detected as an etiology initially, followed by the detection of epilepsy as another etiology. Clinicians should consider possibility of two or more etiologies in a single recurrent ALTE case. Yoshihiko Takano, Masaki Horiike, Ako Tatsumi, Haruko Sakamoto, Hisanori Fujino, and Shin-ichi Sumimoto Copyright © 2016 Yoshihiko Takano et al. All rights reserved. Hydropneumothorax in Children: A Rare Complication of a Bacterial Pneumonia Mon, 09 May 2016 12:03:24 +0000 http://www.hindawi.com/journals/cripe/2016/8097105/ Hydropneumothorax is an uncommon presentation of a complicated pneumonia, and very few cases in the pediatric population have been reported. This is a case of a 5-month-old patient who presented to the emergency department (ED) with a three-day history of fever, diarrhea, and respiratory distress. His initial assessment suggested a lower respiratory tract infection and because of his respiratory distress and hypoxia a chest X-ray was performed. Other clinical information and radiologic studies will be discussed further, but his chest X-ray suggested a right-sided hydropneumothorax secondary to a complicated pneumonia. He completed 12 days of IV antibiotic treatment and required a chest tube for drainage. Patient was discharged home with a full recovery. Carolina Ortega, Carla Gonzales, Manuel E. Soto-Martinez, and Adriana Yock-Corrales Copyright © 2016 Carolina Ortega et al. All rights reserved. Solitary Myofibroma of the Bladder Trigone in a 3-Month-Old Patient: First Case Report Tue, 03 May 2016 08:50:01 +0000 http://www.hindawi.com/journals/cripe/2016/1951840/ Visceral solitary myofibromas are uncommon in childhood. We report a case of a solitary asymptomatic visceral myofibroma of the bladder trigone occurring in a 3-month-old boy. Once malignancies were ruled out by cystoscopy, radical excision was performed in order to avoid any potential impairment of bladder dynamic. Postoperative course was uneventful and patient was discharged on day 3 after surgery. After 36 months of follow-up, the patient is toilet-trained and remains well; bladder function is normal. Marco Pensabene, Fortunato Siracusa, Vito Rodolico, Giuseppe Li Voti, Elisa Zambaiti, and Marcello Cimador Copyright © 2016 Marco Pensabene et al. All rights reserved. Huge Congenital Segmental Dilatation of the Sigmoid Colon in a Neonate: A “Rarity to Meet” and a “Challenge to Treat” Thu, 28 Apr 2016 14:07:17 +0000 http://www.hindawi.com/journals/cripe/2016/9685307/ Only ten cases of neonatal congenital segmental dilatation (CSD) of the colon have been described so far. We present a full-term female newborn with trisomy 21, ventricular septal defect, and gross abdominal distension. Plain abdominal radiographs revealed a huge cystic lesion occupying the left hemiabdomen. Upon laparotomy on day 4 a CSD of the distal sigmoid and proximal rectum was confirmed and resected. The proximal colon was exteriorized and the distal part closed as a Hartmann pouch. Histology confirmed a huge segmental dilatation of the sigmoid without dysganglionosis or pseudodiverticula, but normal intestinal architecture. After correction of the ventricular septal defect a low rectal end-to-end anastomosis could be performed at an age of 5 months. The postoperative course was uneventful. CSD of the sigmoid colon is extremely “rare to meet” and a “challenge to treat” in the newborn period, but clinical awareness of this entity prompts pediatric surgical success. Margarita Kaiser, Christoph Castellani, Georg Singer, Robert Marterer, Manfred Ratschek, and Holger Till Copyright © 2016 Margarita Kaiser et al. All rights reserved. Sporadic Burkitt Lymphoma Presenting as Acute Pancreatitis, Concurrent Sinusitis, and Enlarged Adenoids Sun, 24 Apr 2016 13:23:32 +0000 http://www.hindawi.com/journals/cripe/2016/3862175/ Pancreatitis and sinusitis as presentations of Burkitt lymphoma are uncommon and rarely described in children. We describe here the case of a child who presented with symptoms suggestive of sinusitis unresponsive to antibiotics, with subsequent development of abdominal symptoms due to pancreatitis. He was eventually diagnosed with Burkitt lymphoma. Vasudha Mahajan, You-Wen Qian, Brooke Blake, Yesenia Rojas-Khalil, Ravi S. Radhakrishnan, and Akila Muthukumar Copyright © 2016 Vasudha Mahajan et al. All rights reserved. Cerebral Salt Wasting Syndrome following Head Injury in a Child Managed Successfully with Fludrocortisone Sun, 24 Apr 2016 13:10:02 +0000 http://www.hindawi.com/journals/cripe/2016/6937465/ Cerebral salt wasting (CSW) syndrome is an important cause of hyponatremia in head injuries apart from syndrome of inappropriate antidiuretic hormone (SIADH). Proper diagnosis and differentiation between these two entities are necessary for management as the treatment is quite opposite in both conditions. Fludrocortisone can help in managing CSW where alone saline infusion does not work. We report a 17-month-old female child with head injury managed successfully with saline infusion and fludrocortisone. Nagendra Chaudhary, Santosh Pathak, Murli Manohar Gupta, and Nikhil Agrawal Copyright © 2016 Nagendra Chaudhary et al. All rights reserved. Acute Alithiasic Cholecystitis and Human Herpes Virus Type-6 Infection: First Case Wed, 20 Apr 2016 06:51:26 +0000 http://www.hindawi.com/journals/cripe/2016/9130673/ A three-year-old male child presented with erythematous maculopapular nonpruritic generalized rash, poor feeding, vomiting, and cramping generalized abdominal pain. He was previously healthy and there was no family history of immunologic or other diseases. On examination he was afebrile, hemodynamically stable, with painful palpation of the right upper quadrant and positive Murphy’s sign. Laboratory tests revealed elevated inflammatory markers, elevated aminotransferase activity, and features of cholestasis. Abdominal ultrasound showed gallbladder wall thickening of 8 mm with a positive sonographic Murphy’s sign, without gallstones or pericholecystic fluid. Acute Alithiasic Cholecystitis (AAC) was diagnosed. Tests for underlying infectious causes were negative except positive blood specimen for Human Herpes Virus Type-6 (HHV-6) by polymerase chain reaction. With supportive therapy the child became progressively less symptomatic with gradual improvement. The child was discharged on the sixth day, asymptomatic and with improved analytic values. Two months later he had IgM negative and IgG positive antibodies (1/160) for HHV-6, which confirmed the diagnosis of previous infection. In a six-month follow-up period he remains asymptomatic. To the best of our knowledge, this represents the first case of AAC associated with HHV-6 infection. Maria Miguel Gomes, Henedina Antunes, Ana Luísa Lobo, Fernando Branca, Jorge Correia-Pinto, and João Moreira-Pinto Copyright © 2016 Maria Miguel Gomes et al. All rights reserved. Successful Treatment of Bacillus cereus Bacteremia in a Patient with Propionic Acidemia Tue, 19 Apr 2016 14:06:43 +0000 http://www.hindawi.com/journals/cripe/2016/6380929/ Bacillus cereus can cause serious, life-threatening, systemic infections in immunocompromised patients. The ability of microorganism to form biofilm on biomedical devices can be responsible for catheter-related bloodstream infections. Other manifestations of severe disease are meningitis, endocarditis, osteomyelitis, and surgical and traumatic wound infections. The most common feature in true bacteremia caused by Bacillus is the presence of an intravascular catheter. Herein, we report a case of catheter-related bacteremia caused by B. cereus in a patient with propionic acidemia. Fatma Deniz Aygun, Fatih Aygun, and Halit Cam Copyright © 2016 Fatma Deniz Aygun et al. All rights reserved. Reticulated, Hyperchromic Rash in a Striated Pattern Mimicking Atopic Dermatitis and Fungal Infection in a 2-Month-Old Female: A Case of Incontinentia Pigmenti Tue, 19 Apr 2016 09:23:50 +0000 http://www.hindawi.com/journals/cripe/2016/9512627/ We present a 12-month-old Hispanic female with a reticulated, hyperchromic rash in a striated pattern appearing on upper and lower extremities and trunk and back since the age of 6 weeks. Over the next 10 months, the rash persisted. The rash did not respond to treatment with antifungals and steroids. During her 6-month wellness visit, the patient was diagnosed with incontinentia pigmenti (IP), a rare X-linked dominant disorder, fatal to male fetuses in utero. IP can lead to serious neurological and ophthalmologic consequences. Early diagnosis by primary care physicians and parental education about the condition are essential for prevention of retinal detachment, developmental delay, and dental abnormalities. Nina Poliak, Alexandre Le, and Anthony Rainey Copyright © 2016 Nina Poliak et al. All rights reserved. Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect: An Unusual Predisposition Mon, 18 Apr 2016 07:25:49 +0000 http://www.hindawi.com/journals/cripe/2016/7026068/ Candida parapsilosis is emerging as a potential pathogen for onychomycosis. A 4-year-old male child with perimembranous ventricular septal defect (VSD) was admitted with features of cystitis and was treated with broad spectrum antibiotics. Two weeks later, he developed yellowish discoloration of nails of both hands. The sloughed out nail, on microscopy, showed numerous yeast forms that were identified as Candida parapsilosis by both phenotypic and genotypic methods. Antifungal sensitivity testing of the isolate was performed by microbroth dilution method in accordance with CLSI guidelines. Patient was successfully treated with topical amphotericin B and oral fluconazole. Thus, one should have a high index of suspicion of C. parapsilosis onychomycosis, especially when the patient is in the paediatric age group, presenting with unusual predisposing condition like congenital heart disease, and is on broad spectrum antibiotics. Supram Hosuru Subramanya, Deependra Hamal, Niranjan Nayak, and Shishir Gokhale Copyright © 2016 Supram Hosuru Subramanya et al. All rights reserved. Clostridium difficile Enterocolitis and Reactive Arthritis: A Case Report and Review of the Literature Thu, 14 Apr 2016 07:36:37 +0000 http://www.hindawi.com/journals/cripe/2016/1591753/ Reactive arthritis is a rare complication of Clostridium difficile enterocolitis, especially in children. We review the 6 pediatric cases published in the English and non-English literature and discuss their clinical presentation, outcome, treatment, and pathophysiology. We also report the seventh case of Clostridium difficile reactive arthritis in a 6-year-old boy who was treated with amoxicillin-clavulanate for 10 days because of an upper respiratory infection. After the antibiotic course, the child developed at the same time diarrhea with positive stool culture for Clostridium difficile and an asymmetric polyarthritis. Nonsteroidal anti-inflammatory drugs and metronidazole completely resolved the pain, joint swelling, and diarrhea. After twelve months of follow-up there has been no recurrence. This report confirms the self-limiting course of Clostridium difficile reactive arthritis. Clostridium difficile testing in children with gastrointestinal symptoms and acute onset of joint pain should be always considered. Michela Cappella, Fabrizio Pugliese, Andrea Zucchini, and Federico Marchetti Copyright © 2016 Michela Cappella et al. All rights reserved. Impact of Heart Transplantation on Cheyne-Stokes Respiration in a Child Tue, 05 Apr 2016 13:39:50 +0000 http://www.hindawi.com/journals/cripe/2016/4698756/ Sleep disordered breathing is well described in adults with heart failure but not in pediatric population. We describe a 13-year-old Caucasian male with severe heart failure related to dilated cardiomyopathy who demonstrated polysomnographic features of Cheyne-Stokes respiration, which completely resolved following cardiac transplantation. Cheyne-Stokes respiration in children with advanced heart failure and its resolution after heart transplant can be observed similar to adults. Suhail Al-Saleh, Paul F. Kantor, and Indra Narang Copyright © 2016 Suhail Al-Saleh et al. All rights reserved. Metastatic Colon Cancer in an 18-Year-Old without Predisposing Factors Sun, 27 Mar 2016 08:51:12 +0000 http://www.hindawi.com/journals/cripe/2016/7820367/ While colorectal carcinoma is a common gastrointestinal cancer in adults, it is rare in pediatrics with an incidence of 1 : 1,000,000 and represents a fraction of neoplasms encountered in children. Malignant neoplasms represent a major cause of mortality in the pediatric age group. While presenting with weight loss, iron deficiency, rectal bleeding, abdominal pain, and change in bowel habits, or symptoms similar to acute appendicitis, the working diagnosis may be considered to be anorexia. This case illustrates the importance of considering colon cancer among other disease entities as a cause of unintentional weight loss in adolescents. While this is a rare occurrence in the pediatric population, significant unintentional weight loss with altered bowel habits should prompt a search for underlying malignancy—even in the absence of a positive family history or predisposing cancer syndromes. Divya Mirchandani, Jolanta Kulpa, Nayaab Khawar, Israel Kochin, Pramod Narula, and Revathy Sundaram Copyright © 2016 Divya Mirchandani et al. All rights reserved. Neonatal Abdominal Hemangiomatosis: Propranolol beyond Infantile Hemangioma Sun, 27 Mar 2016 07:56:14 +0000 http://www.hindawi.com/journals/cripe/2016/9803975/ Hemangioma is the most common vascular tumor of infancy; presentation is often as cutaneous infantile hemangioma (IH). Cutaneous hemangioma is a clinical diagnosis. Most IHs follow a benign course, with complete involution without treatment in the majority of cases. Visceral hemangioma often involves the liver and manifests as a life-threatening disorder. Hepatic hemangiomas may be associated with high output cardiac failure, coagulopathy, and hepatomegaly which generally develop between 1 and 16 weeks of age. Mortality has been reportedly high without treatment. We report a rare case of a male infant with neonatal hemangiomatosis with diffuse peritoneal involvement, which mimicked a malignant-looking tumor on imaging, and discuss therapeutic options and efficacy. Propranolol is efficacious for IH but generally not useful for other forms of vascular hemangiomas, tumors, and malformations. In our case of neonatal peritoneal hemangiomatosis, propranolol appears to have halted the growth and possibly expedite the involution of the hemangiomatosis without other treatments. Siu Ying Angel Nip, Kam Lun Hon, Wing Kwan Alex Leung, Alexander K. C. Leung, and Paul C. L. Choi Copyright © 2016 Siu Ying Angel Nip et al. All rights reserved. Pancreatic Cystosis in Two Adolescents with Cystic Fibrosis Thu, 24 Mar 2016 11:05:22 +0000 http://www.hindawi.com/journals/cripe/2016/5321785/ We present pancreatic cystosis in two adolescents with cystic fibrosis, a 13-year-old girl and an 18-year-old boy. In pancreatic cystosis, which is a rare manifestation of CF, the pancreatic parenchyma is replaced with multiple cysts of different sizes. Pancreatic cystosis is mainly an imaging based diagnosis and frequent follow-up should be recommended. Elpis Hatziagorou, Asterios Kampouras, Maria Sidiropoulou, Andreas Markou, Athanasia Anastasiou, and John Tsanakas Copyright © 2016 Elpis Hatziagorou et al. All rights reserved. An Interesting Association of Cystic Hygroma of the Neck and Lymphangioma Causing a Paediatric Swollen Tongue Wed, 16 Mar 2016 07:51:44 +0000 http://www.hindawi.com/journals/cripe/2016/7930945/ Up to 75% of lymphatic malformations occur in the head and neck region. Of these, cystic hygromas and lymphangiomas have been widely reported; however they rarely occur in the same patient. We report the case of a 5-year-old girl who presented to the Department of Paediatrics of a district general hospital with a short history of recurrent, painful swelling of the anterior one-third of her tongue. She was reviewed under the joint care of the Oral and Maxillofacial Surgery and Otolaryngology Teams. Relevant past medical history included a previously excised cystic hygroma from her right neck when she was aged 2 years. Diagnosis of lymphangioma was made and of the potential management options available active monitoring was favoured due to the patient’s age. To our knowledge the occurrence of both tongue lymphangioma and cystic hygroma has not been previously reported in a paediatric patient. This case report therefore shows a rare association between a cystic hygroma of the neck and lymphangioma of the tongue. A. N. Beech and J. N. Farrier Copyright © 2016 A. N. Beech and J. N. Farrier. All rights reserved.