Psychosis or Obsessions? Clozapine Associated with Worsening Obsessive-Compulsive Symptoms

Figure 1

Brief overview of OCD pathophysiology and suspected targets involving antipsychotic-induced OCS/OCD. ACC: anterior cingulate cortex; DLPC: dorsal lateral prefrontal cortex; GPe: globus pallidus pars externalis; GPi: globus pallidus pars internalis; OFC: orbitofrontal cortex; STN: subthalamic nucleus; SNc: substantia nigra pars compacta; SNr: substantia nigra pars reticulata; VTA: ventral tegmental area.