Case Report

A Case of Sporadic Creutzfeldt-Jakob Disease Presenting as Conversion Disorder

Table 1

Centers for disease control and prevention’s diagnostic criteria for sCJD.

ABC

() Myoclonus
() Visual or cerebellar signs
() Pyramidal/extrapyramidal signs
() Akinetic mutism
() Periodic sharp wave complexes on EEG during an illness of any duration
() Positive 14-3-3 CSF assay in patients with a disease duration of less than 2 years
() MRI high signal abnormalities in caudate nucleus and/or putamen on diffusion weighted or fluid attenuation inversion recovery imaging
Routine investigations that do not indicate an alternative diagnosis

Definite sCJD = diagnosed by standard neuropathological techniques; and/or immunocytochemically and/or Western blot confirmed protease-resistant PrP and/or presence of scrapie-associated fibrils.
Probable sCJD = rapidly progressive dementia + at least 2 of (A) + at least 1 of (B) + (C).
Possible sCJD = progressive dementia with duration of illness less than 2 years + at least 2 of (A) + none of (B) + (C).