Case Report

Goodpasture’s Syndrome and p-ANCA Associated Vasculitis in a Patient of Silicosiderosis: An Unusual Association

Table 1

Laboratory investigations.

Haemoglobin4.8 g/dL

Total leucocyte count6400/mm3

Differential leucocyte count (N/L/M/E)74/20/5/1

Platelets81,000/mm3

Urine routine examination4+ albumin,
12–15 red blood cells
2–4 Pus cells.

Renal function testsBlood Urea—165 mg/dL
Serum Creatinine—4.7 mg/dL

Serum CPKMB11 U/L

Serum LDH754.8 U/L


ANCA
pANCA-Positive
Indirect immunofluorescence (IIF): perinuclear positivity
ELISA (Euroimmun kit)-positive
cANCA-negative

Anti-GBMELISA-negative