Case Report

Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis

Figure 4

MRS (Philips Achieva 3T, TR/TE = 2000/40, increased choline, inverted Cho/Cr ratio, decreased N-acetyl-aspartate between December 2011 (a) and May 2012 (b) of the white matter lesion underneath the frontal lobe of the left hemisphere (arrows) at MRS in a 44-year-old man with a 12-year history of MS affected by natalizumab-related PML. May 2012 MRS showed a decrease in Cho/Cr ratio and increased N-acetylaspartate.
415873.fig.004a
(a)
415873.fig.004b
(b)