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Case Reports in Rheumatology
Volume 2012 (2012), Article ID 724013, 4 pages
http://dx.doi.org/10.1155/2012/724013
Case Report

Pulmonary Sarcoidosis following Etanercept Treatment

Department of Rheumatology, Wycombe General Hospital, Queen Alexander Road, Wycome, Buckinghamshire HP11 2TT, UK

Received 31 October 2012; Accepted 26 November 2012

Academic Editors: S. S. Koca and S. C. Plastiras

Copyright © 2012 Kuljeet Bhamra and Richard Stevens. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Tumour necrosis factor (TNF) is an important cytokine involved in the pathology of a number of inflammatory conditions, and thus blockade with anti-TNF therapies is becoming the cornerstone in managing such diseases. With increasing use, evidence is collected for the association of sarcoid-like granulomatous disease developing after the initiation of anti-TNF-α therapy, with disease reversal after discontinuation.