RHUPUS Syndrome in Children: A Case Series and Literature Review

Table 1

Clinical and paraclincal features and outcome of cases with RHUPUS syndrome in this case report and previous reports in children.

Report	Sex	JIA Characteristics					Delay in SLE diagnosis (mo)^†
		Age at onset (y)	ANA	RF	Subtype	Erosion
Unsal et al. [10]	Female	8.5	−	−	Oligoarticular	No	24
Bazsó et al. [4]	Female	12	−	−	Polyarticular	No	120
	Female	10	+	+	Polyarticular	No	11
Cavalcante et al. [5]	Female	10	+	+	Polyarticular	Yes	9
	Male	5	+	+	Polyarticular	Yes	15
Takei et al. [11]	Female	15	−	−	Polyarticular	No	96
	Female	3	−	−	Polyarticular	?	120
Martini et al.* [12]	Female	5	?	?	?	?	72
	Female	8	+	+	Oligoarticular	Yes	24
Our study	Female	10	+	+	Polyarticular	Yes	24
	Male	11	−	+	Oligoarticular	No	36
Total cases	82% female	8.1	50% positive	60% positive	70% polyarticular	45% erosion	50.1

∗We did not access full text of this report.
^†Delay between beginning of chronic arthritis and SLE diagnosis.