Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review

Table 3

Characteristics of patients with CMV infection and vascular thrombosis associated with aPL.

Patient	Age/Sex	Diagnostic method of CMV infection	Site of thrombosis	Type of aPL	Reference
1	35/M	lgM+, viruria	Superior mesenteric vein, femoropopliteal vein	IgM aCL, IgG aCL (2GPI-dependent)	[17]
2	32/F	lgM+	Iliac vein	IgM aCL	[13]
3	79/F	lgM+, antigenemia+	Pulmonary artery	IgG aCL	[14]
4	30/M	lgM+, antigenemia+	Portal vein	IgM aCL	[15]
5	24/F	lgM+ (antigenemia−)	Superior mesenteric vein, pulmonary artery	IgM aCL	[16]
6	30/F	lgG+, mononucleosis-like syndrome	Middle cerebral artery	IgM aCL, IgG aCL,; IgM anti-2GPI,; IgG anti-2GPI	[18]
Present case	19/F	lgM+, real-time PCR	Inferior vena cava, posterior tibial vein, pulmonary artery	LAC	—

aCL: anticardiolipin antibodies; aPL: antiphospholipid antibodies; 2GPI: 2 glycoprotein I; CMV: cytomegalovirus; LAC: lupus anticoagulant.