Case Report

Acute Hemorrhagic Myositis in Inflammatory Myopathy and Review of the Literature

Table 1

Clinical features of selected case reports of hemorrhagic myositis in inflammatory myopathies.

AuthorAge (yrs)
(at event)
GenderClinical history and prebleeding therapiesAntibody
profile
Site of bleeding(s)TreatmentOutcome
(as reported)

Orrell et al. [7]50FemaleDM age 34
Corticosteroid
Azathioprine
IVIG
None specifiedLeft rectus abdominisBlood transfusions Prednisone AzathioprineSurvived, no recurrent bleeding

Orrell et al. [7]11FemaleDM age 8
Prednisone
ANA 1 : 320
speckled
Retroperitoneum,
posterior to right
ascending colon
SupportiveSurvived without recurrence

Fang et al. [8]65FemalePM age 65
Hydrocortisone
Prednisone
ANA 1 : 320
speckled
Retroperitoneum,
superior duodenal pancreatic artery,
SMA
Angiography with embolizationExpired from sepsis without rebleeding

Yamagishi et al. [9]64FemaleDM/ILD age 64
Solumedrol
Prednisone
Cyclosporine
Dalteparin
ANA positive
Elevated
serum KL-6
Retroperitoneum,
right psoas,
right iliacus,
left rectus sheath
Angiography with embolization with rebleeding and repeat embolizationExpired from TTP and multiorgan failure

Higashi et al. [10]77FemaleDM age 77
Solumedrol
Prednisone
Cyclosporine
Heparin
Elevated
serum KL-6
Retroperitoneum,
left iliopsoas,
left iliacus,
right sternomastoid
SupportiveExpired from DIC

Van Gelder et al.50MaleDM/ILD age 50
Solumedrol
IVIG
Anti-Ro52Retroperitoneum,
right iliacus,
right psoas
Transfusions
Solumedrol
Expired from multiorgan failure

Van Gelder et al.63FemaleDM/ILD age 63
Solumedrol
IVIG
Anti-SSA
Anti-Ro52
Retroperitoneum,
right pectineus,
right iliopsoas
Transfusions
Solumedrol
Cytoxan
Expired from multiorgan failure