A Case of Multicentric Carcinoid in a Patient with Psoriatic Spondyloarthropathy

Figure 2

Biopsy specimens from lung (a) and rectal polyp (b). (a) Histological analysis of lung lesion revealed columnar cells with bland nuclei arranged in an insular pattern with infrequent mitoses. Staining for neuron-specific enolase, synaptophysin, and CD56 was highly positive, but negative for chromogranin A and S100, suggestive of typical carcinoid neoplasia. (b) Rectal polyp analysis showed well circumscribed growth of uniform polygonal cells with round nonmitotic nuclei and speckled chromatin with nested and acinar growth pattern; features indicative of a benign endocrine tumour. Histologically, the specimen from the rectum was not suggestive as being related to the lung lesion, hence the labelling of this case as “multicentric.”

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