Polyarteritis Nodosa Presenting as Digital Gangrene and Breast Lesion following Exposure to Silicone Breast Implants

Figure 2

Necrotizing cutaneous polyarteritis nodosa. (a) and (b) exhibit a nodule of arteritis in the subcutis (arrows). (c) and (d) show extensive arterial damage seen as both angiodestructive inflammation and thrombotic occlusion. (e) highlights vascular congestion and extensive coagulative necrosis of epidermis and dermal adnexae. Extensive necrosis of adipocytes (see (c)) was also found indicating that arteritis caused significant ischemic damage to the surrounding tissues.