Case Report

Herpes Zoster Meningitis Complicating Combined Tocilizumab and Cyclosporine Therapy for Adult-Onset Still’s Disease

Table 1

Laboratory findings.

Peripheral blood Serological tests 
 Red blood cells406 × 104/μL C-reactive protein <0.30 mg/dL
 Hemoglobin10.5 g/dL Erythrocyte sedimentation rate3.0 mm/hr
 White blood cells9600/μL IgG 883 mg/dL (900–2000)
  St23.0% Ferritin613 ng/mL (10–85)
  Seg66.0% C3108 mg/dL (4–64)
  Ly6.0% C424 mg/dL (17–45)
  Mo4.0% CH5042.7 U/mL (30–50)
  AtyLy1.0% Anti-nuclear Ab<×40
 Platelet12.1 × 104/μL Anti-CCP Ab<0.6 U/mL (<4.5)
Blood chemistry β-D-glucan(−)
 Total protein 5.9 g/dL 
 Albumin3.9 g/dLCSF 
 Total bilirubin 0.6 mg/dL Cell number55/mm3
 Glutamic-oxaloacetic transaminase176 IU/L (7–33)  Neutrophils3%
 Glutamic-pyruvic transaminase181 IU/L (5–30)  Monocytes97%
 Lactate dehydrogenase518 IU/L (260–480)  
 Alkaline phosphatase271 IU/L (80–250) Protein92 mg/dL
 Creatinine kinase21 IU/L (60–160) Sugar45 mg/dL
 Total cholesterol217 mg/dL Cl103 mEq/L
 Blood urea nitrogen10.8 mg/dL Herpes zoster DNA (PCR method)(+)
 Creatinine 0.4 mg/dL
 Na128 mEq/L
 K3.5 mEq/L
 Cl95 mEq/L

Anti-CCP Ab, anti-cyclic citrullinated peptide antibody; CSF, cerebrospinal fluid; PCR, polymerase chain reaction.