Case Report
Heparin-Related Thrombocytopenia Triggered by Severe Status of Systemic Lupus Erythematosus and Bacterial Infection
Table 1
Laboratory test findings.
| | Test | Result |
| | Blood cell count | WBC 1000/μL | | Neu 505/μL | | Lym 100/μL | | Eosi 0/μL | | RBC 280万/μL | | Hb 6.9 g/dL | | Hct 24.3% | | Plt 10000/μL |
| | Coagulation | PT 114% | | (PT-INR 0.95) | | APTT 30.5 sec | | FDP 25.2 μg/mL |
| | Biochemistry | T-Bil 0.3 mg/dL | | D-Bil 0.1 mg/dL | | AST 22 IU/L | | ALT 11 IU/L | | γ-GTP 21 IU/L | | BUN 62 mg/dL | | Cre 2.46 mg/dL | | eGFR 23.31 | | UA 10.4 mg/dL | | Na 134 mEq/L | | K 5.0 mEq/L | | Cl 105 mEq/L | | TP 5.0 g/dL | | Alb 1.9 g/dL |
| | Serology | CRP 1.87 mg/dL | | ANA ×320 | | Homogeneous ×320 | | Speckled ×320 | | Anti-DNA antibody 300 IU/mL | | Anti-RNP antibody (−) | | Anti-SS-A antibody (−) | | Anti-cardiolipin antibody (IgG) 16 IU/mL | | CH50 12/mL | | C3 24 mg/dL | | C4 5 mg/dL | | IgG 1554 mg/dL | | IgA 148 mg/dL | | IgM 290 mg/dL |
| | Urinalysis | pH 5.0 | | Protein (4+) | | Ketone body (−) | | Occult blood (±) |
| | Urinary sediment | RBC 10–19 HPF | | WBC 20–29 HPF | | Hyaline cast (2+) | | Epithelial cast (1+) | | Granular cast (1+) | | Waxy cast (1+) |
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WBC: white blood cell, RBC: red blood cell, Hb: hemoglobin, Hct: hematocrit, Plt: platelet, PT: prothrombin time, INR: international normalized ratio, APTT: activated partial thromboplastin time, FDP: fibrinogen and fibrin degradation products, Bil: bilirubin, AST: aspartate transaminase, ALT: alanine transaminase, BUN: blood urea nitrogen, eGFR: estimated glomerular filtration rate, TP: total protein, CRP: C-reactive protein, ANA: anti-nuclear antibody, LAC: lupus anticoagulant, CH50: total complement activity, Ig: immunoglobulin, and HPF: high power field.
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