Case Report

A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma

Table 1

Autoimmune laboratory results.

LabsValueNormal range

ESR120 mm/hr0–29 mm/hr
CRP8.81.0–10.0 mg/L
Creatine kinase116230–223 U/L
ANA ratio2.850.00–0.99
Nucleolar pattern1 : 3201 : 40
ANCA myeloperoxidase<0.90.0–9.0 U/mL
ANCA proteinase 3<3.50.0–3.5 U/mL
Atypical P-ANCA<1 : 20Negative < 1 : 20 titer
Anti-centromere antibody<0.20.0–0.9 AI
Double stranded DNA 10–9 IU/mL
C3 complement13987–200 mg/dL
C4 complement2919–52 mg/dL
Anti-Jo-1NegativeNegative
SCL-70 antibodyNegativeNegative
SM antibodyNegativeNegative
SM/RNP antibodiesNegativeNegative
Anti-SSA/SSB antibodiesNegativeNegative
Anti-RNA polymerase III antibody33.6<20 units/mL
Anti-Th/ToNegativeNegative
Anti-U3RNPNegativeNegative
Anti-U1RNP<20<20

ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; ANA: anti-nuclear antibody; ANCA: anti-neutrophil cytoplasmic antibodies.