Case Report

An Unusual Case of Systemic Lupus Erythematosus and Hemophagocytic Syndrome

Table 3

Autoimmune and infectious workup.

VariableMeasurementReference range

ANAPositiveNegative
ANA, quantitative1 : 160Negative
ANA, patternSpeckledNegative
ds DNA ab IgG Titer300 or greater0–29 IU/ML
C32390–180 mg/dL
C4310–40 mg/dL
Anti-Smith (Sm) interp.Negative Negative
SM-RNP antibodies interp.Negative Negative
SM-RNP ab interp.Negative Negative
Smith (ENA) ab, IgG 0.8<16.00 EU/mL
SSA (Sjogren ab)0.7<16.00 EU/mL
SSB (Sjogren ab)1<16.00 EU/mL
Ribosomal P ab <1.0Negative
Smooth muscle abNegative Negative
LKM 1 ab IgG<20.0 UNegative
GBM ab IgG <1.0<1.0 AI no antibody detected
Histone ab 1.2<1.0 U negative
Cardiolipin ab IgM24Low to medium positive
Cardiolipin ab IgG20Indeterminate
β2-Glycoprotein I IgMNegative Negative
β2-Glycoprotein I IgA 9Negative
ANCA vasculitides
 Proteinase 3 ab<1.0 <1.0
 Myeloperoxidase ab<1.0<1.0
Hep A ab, IgMNonreactiveNonreactive
Hep A ab, total NonreactiveNonreactive
Hep B sAgNegativeNegative
Hep B Core ab, totalReactiveNonreactive
Hep BS abReactiveNonreactive
Hep C abNegativeNegative
HIV 1/2 ab screen, rapidNonreactiveNonreactive
Cytomegalovirus, IgM 0.7<0.9
Cytomegalovirus, Igg NegativeNegative
EBV, DNA, QN, and PR-PCR<200 COPIES/MLNegative
Syphilis Screen TiterNonreactiveNonreactive
Lyme Disease ab Screen0.58<0.91
RMSF IgM and IgG Not detectedNot detected
B. Quintana IgM ScrNegativeNegative
B. Quintana IgG Scr NegativeNegative
B. Henselae ab IgGNegativeNegative
Brucella IgG 0.16<0.80 antibody not detected
Brucella IgM 0.07<0.80 antibody not detected
AFB cultureNegativeNegative
Fungal cultureNegativeNegative
Viral cultureNo virus isolated after 4 daysNegative
Gram stainFew 2+ PMN no organismsNegative
Bacterial cultureNo growthNegative