(9) Hemophagocytosis features on bone marrow aspirate: 0 (no) or 35 (yes)
Then, measure the assigned probability‡
HScore
Probability of hemophagocytic syndrome, %
90
<1
100
1
110
3
120
5
130
9
140
16
150
25
160
40
170
54
180
70
190
80
200
88
210
93
220
96
230
98
240
99
250
>99
Human immunodeficiency virus positive or receiving long-term immunosuppressive therapy (i.e., glucocorticoids, cyclosporine, and azathioprine). †Defined as a hemoglobin level of ≤9.2 g/dl and/or a leukocyte count of ≤5000 cells/µL and/or a platelet count of ≤110,000 cells/µL. ‡The best cutoff value for HScore was 169, corresponding to a sensitivity of 93%, a specificity of 86%, and accurate classification of 90% of the patients. Table 3 is copied from Fardet et al. [19].