Clinical and Diagnostic Considerations for Atypical, Adult Onset Presentation of Chronic Recurrent Multifocal Osteomyelitis (CRMO)

Figure 7

Bone biopsy of the left medial clavicle performed on 1/21/2019. (a) H&E 200x marrow fibrosis with plasma cell infiltrate. (b) H&E 400x marrow fibrosis (lighter purple color throughout indicated by black arrow) in place of a fatty marrow background with plasma cell infiltrate that contains eccentric nuclei (area indicated by white arrow) representing changes indicative of chronic inflammation.

(a)

(b)