Case Report
Sensory-Motor Polyneuropathy and Digital Ischemia: A Rare Presentation of Granulomatosis with Polyangiitis
Table 1
Summary of investigations.
| Investigation | Value | Reference range |
| White cell count | 9300 | 4,000–11,000 cells/μL | Neutrophils | 6600 | 2,000–7,000 cells/μL | Lymphocytes | 1120 | 1,000–4,000 cells/μL | Hemoglobin | 12.0 | 12–16 g/dL | Platelets | 177,000 | 150,000–450,000/μL | Blood film | No abnormal cells seen. Within normal limits | | Serum creatinine | 65 | 70–110 μmol/L | Sodium | 136 | 135–145 mmol/L | Potassium | 4.2 | 3.5–4.5 mmol/L | AST | 20 | <40 U/L | ALT | 25 | <35 U/L | Albumin | 35 | 35–45 g/L | Globulin | 38 | 30–40 g/L | ALP | 106 | 30–120 U/L | ESR | 110 | <20 mm/1st hour | CRP | 36 | <6 mg/L | Rheumatoid factor | <8 | <8 IU/L | Antinuclear antibodies | Negative | | HIV 1 and 2 antigens/antibodies | Negative | | c-ANCA | Positive | | p-ANCA | Negative | | Anti-Smith antibody | Negative | | Anti-Scl-70 antibody | Negative | | Anti-Ro antibody | Negative | | Anti-La antibody | Negative | | Lupus anticoagulant | Negative | | Anticardiolipin antibody, IgM | Negative | | Anti-ß2 glycoprotein antibodies, IgM and IgG | Negative | | Serum complement level | Normal | | Serum cryoglobulin | Negative | | Hepatitis C antibody | Negative | | Hepatitis B surface antigen | Negative | | Urine full report | Normal | | Chest X-ray | No abnormality detected | | Ultrasound abdomen | Normal | | 2D echocardiogram | No abnormality detected including any cardiac source of emboli | | HbA1C | 6.0% | |
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AST, aspartate transaminase; ALT, alanine transaminase; ALP, alkaline phosphatase; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; TSH, thyroid stimulating hormone; HIV, human immunodeficiency virus; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibody; p-ANCA, perinuclear antineutrophil cytoplasmic antibody.
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