Ocular Melanoma Metastasizing to Intra-Abdominal Lymph Nodes
Figure 3
Low magnification (a) and high magnification (b) sections from the core needle biopsy showed connective tissue and a small amount of lymphoid tissue massively infiltrated by a malignant process composed of large, atypical cells with eosinophilic cytoplasm, vesicular nuclei with prominent nucleoli (hematoxylin and eosin). MART-1 immunostain confirmed the diagnosis of metastatic melanoma (c). In the resected specimen, lymph nodes matted together were almost completely replaced by metastatic melanoma with extensive areas of necrosis (arrows) ((d), low magnification, hematoxylin and eosin; (e), confirmatory MART-1 immunostain).
