Synchronous Bilateral Solid Papillary Carcinomas of the Breast
Figure 2
(a) Tumor 1 and the adjacent SPC. The SPC is shown on the upper half (cross), while invasive ductal carcinoma is shown on the lower half (star) (hematoxylin-eosin, original magnification ×10). (b) Tumor 1 was diagnosed as invasive ductal carcinoma NOS. Small alveolar tumor cells structured in a linear growth pattern with fibrosis were observed (hematoxylin-eosin, original magnification ×40). (c) and (d) Tumors 2 and 3 were diagnosed as mucinous carcinomas with tumor cells suspended in abundant cytoplasm mucin (hematoxylin-eosin, original magnification ×10). (e) and (f) SPCs surrounding the bilateral breast. Palisading of tumor cells was evident around the fibrovascular cores. The tumor cells consisted of solid masses of polygonal tumor cells with inconspicuous fibrovascular structures. Extracellular mucin is shown (in the lower portion of 2(e)). The nuclei were small and low grade. Cytoplasmic vacuolization was variably present. Mucicarmine staining demonstrated mucin in the gland lumens and cytoplasm of the tumor cells (hematoxylin-eosin, original magnification ×40).
