Primary Angiosarcoma of the Breast after Bilateral Breast Reduction

Figure 5

(a) 4x CD31 immunohistochemical stain. Positive membranous CD31 highlighting malignant endothelial cells. (b) 10x ERG immunohistochemical stain. Positive nuclear ERG immunostain in the malignant endothelial cells. (c) 10x factor VIII immunohistochemical stain. Positive cytoplasmic stain of malignant endothelial cells. (d) 20x CD34 immunohistochemical stain. Negative CD34, another membranous endothelial cell marker, failing to stain the malignant cells. Pancytokeratin immunostain was also negative.

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