Case Report

Metastasis of Hepatocellular Carcinoma to the Esophagus: Case Report and Review

Table 1

English literature review of esophageal hepatocellular carcinoma metastases.

No.AuthorYearAgeSexSymptomsGross type of esophageal tumorType of hepatitisSerum AFP (ng/ml)Therapy of varicesTherapy for HCCTherapy for esophageal metastasisOther metastasis at livingOutcomeSurvival time (M)

1Sohara200054MMelenaSubmucosalHCV4987Esophageal transection, splenectomyTAILungDeath3
246MHematemesisPolypoidNA990Esophageal transection, EISTACE, radiationDeath7
3Kume200056MDysphagia, tarry stoolSubmucosalHBV12,200EIS, EVLTACELung, boneDeath2
4Cho200350MDysphagia, hematemesisPolypoidNAElevatedResectionRadiation, TAIDeath11
5Tsubouchi200563MNonePolypoidHCV4130+TACEStomachDeath7
6Yan200753MMelenaPolypoidHBV17,036Death1
7Choi200866MMelenaSubmucosal epolypoidNon-B, non-C3.47EVLTACEDeath7
8Xie200850MDysphagia, odynophagiaCauliflower-likeHBVNASystemic chemotherapy, OLT, TACERadiationAlive>7
9Hsu200954MHematemesis, tarry stoolPolypoidHBVNAOLT, TACEStomachDeath4
10Kahn201055MDysphagiaPolypoidHCV1426OLT, TACEHyperthermia, PDT, stent placementDeath10
11Boonnuch201159MDysphagiaSubmucosalNA510OLT, TACEResectionAlive>2
12Fukatsu201263MNonePolypoidNANAEVL, EISTACE, RFADeath1
13Our case71MNonePolypoidHBV1801+ResectionResectionLymph nodeDeath3

HCV: hepatitis C virus; HBV: hepatitis B virus; NA: not available; EIS: endoscopic injection sclerotherapy; EVL: endoscopic variceal ligation; TAI: transcatheter arterial injection; TACE: transcatheter arterial chemoembolization; OLT: orthotopic liver transplantation; RFA: radiofrequency ablation; PDT: photodynamic therapy.