Severe Necrotizing Adenovirus Tubulointerstitial Nephritis in a Kidney Transplant Recipient

Figure 1

Adenovirus tubulointerstitial nephritis. Light microscopy (H&E stain): (a) Severe diffuse interstitial inflammation, (Mag ×200). (b) Granulomatous necrotizing lesions (black arrows). Inflammatory and tubular epithelial cell cast (white arrow) (Mag ×400). Electron microscopy: (c) viral inclusion body in a tubular epithelial cell (×9,500). (d) Viral particles of varying densities (×80,000).

(a)

(b)

(c)

(d)