Case Report
Living Donor Liver Transplantation for Hepatic Venoocclusive Disease/Sinusoidal Obstruction Syndrome Originating from Hematopoietic Stem Cell Transplantation
Table 1
Data of previous reports on liver transplantation for VOD/SOS originating from HSCT.
| | LT type | Age/sex | Conditioning regimens | Time to LT (day) | Follow-up period status | Cause of death |
| Case 1 (11) | Deceased | 55/F | CY/BU | 42 | 54 days | Death | Infection | Case 2 (12) | Deceased | 49/M | CY/BU | 31 | 31 days | Death | MOF | Case 3 (13) | Deceased | 47/M | CY/BU | 41 | 60 days | Death | Infection/MOF | Case 4 (14) | Deceased | 43/M | Etoposide/CY/carmustine | 22/44(1st/2nd) | 70 days | Death | Pneumonia, ARDS/TTP | Case 5 (13) | Deceased | 39/F | CY/BU | 79 | 62 days | Death | Aspergillosis/intracerebral hemorrhage/MOF | Case 6 (15) | Deceased | 38/M | CY/BU | 23 | 8 years | Alive | | Case 7 (16) | Deceased | 35/M | CY/TBI | 43 | 9 months | Alive | | Case 8 (17) | Deceased | 34/F | CY/BU | 21 | 1 year | Alive | | Case 9 (18) | Deceased | 34/F | CY/BU | 35 | 42 days | Death | Interstitial pneumonitis/MOF | Case 10 (19) | Deceased | 33/M | CY/BU | 36 | 3 days | Death | Cerebral edema | Case 11 (19) | Deceased | 32/F | CY/TBI | 39 | 30 days | Death | Pneumonia | Case 12 (19) | Deceased | 31/F | CY/BU | 25 | 213 days | Death | Liver failure | Case 13 (20) | Deceased | 25/M | CY/BU | 32 | 6 months | Death | Pneumocystis pneumonia | Case 14 (21) | Deceased | 23/M | CY/BU | 80 | 140 days | Death | Infection | Case 15 (22) | Living | 2 m/F | CY/TBI | 33 | 9 months | Alive | | Case 16 (23) | Living | 1/F | CY/BU | 84 | 29 months | Alive | | Case 17 (10) | Living | 11 m/M | CY/BU/TBI | 42 | 17 months | Alive | | Our case | Living | 16/F | CY/etoposide/TBI | 84 | 119 days | Death | Sepsis/MOF |
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LT: Liver transplantation; Cy: Cyclophosphamide; BU: Busulfan; TBI: Total body irradiation; MOF: Multiorgan failure; ARDS: Acute respiratory distress syndrome; TTP: Thrombotic thrombocytopenic purpura.
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