354382.fig.004a
(a)
354382.fig.004b
(b)
354382.fig.004c
(c)
Figure 4: (a) Elastica van Gieson staining corresponding to yellow-boxed area in Figure 3(a). The blue arrow indicates area of acute intraplaque hemorrhage close to area of neoangiogenesis. Note that individual erythrocytes are clearly discernible. Black stars indicate thrombotic material. The yellow star indicates surrounding solid fibrotic tissue. (b) Immunohistochemistry of the same region as shown in Figure 3(a) with dense infiltrate of CD68-positive macrophages indicated by red arrows. (c) Immunohistochemistry of same region as shown in Figure 3(a) with infiltrate of CD3-positive T cells indicated by red arrows.