Case Report

Localized Subcutaneous Acute Febrile Neutrophilic Dermatosis in a Dog

Table 1

Protocol of the administered drugs during hospitalization of the dog. All listed drugs were administered from the day of presentation onwards, unless mentioned otherwise.

Drug ingredientDose and form of applicationDuration of application

Antibiotics
 Enrofloxacin a 11 mg/kg per os (PO) q 12 hr6 weeks
 Amoxicillin/clavulanic acid b 20 mg/kg intravenously (IV) q 8 hr5 weeks
 Amoxicillin/clavulanic acid c 12.5 mg/kg PO q 12 hr2 weeks (following IV administration)
 Metronidazole d 15 mg/kg IV q 12 hr1 week
Glucocorticoids
 Dexamethasone e 0.15 mg/kg IV q 12 hr6 days
 Prednisolone f 2 mg/kg PO q 24 hr2 weeks (following dexamethasone), then gradually tapered over 4 weeks
Analgesics
 Fentanyl g 2.5–7.5 μg/kg/hr constant rate infusion (CRI)10 days
 Ketamine h 10 μg/kg/hr CRI8 days
 Buprenorphine i 0.01-0.02 mg/kg subcutaneously q 8 hr3 weeks
 Tramadol j 3 mg/kg PO q 8 hr3 weeks
Gastric protection
 Omeprazole k 1 mg/kg PO q 24 hr7 weeks
 Sucralfate l 30 mg/kg PO q 12 hr10 days
 Metoclopramide m 0.2 mg/kg IV q 6 hr10 days
 Dolasetrone n 0.5 mg/kg q 24 hr7 days
Fluid therapy
 Full electrolyte solution o 1–4 mL/kg/hr CRI4 weeks

a Baytril 2.5%, Provet AG, Lyssach, Switzerland; b Augmentin Adult, Glaxosmithkline, Muenchenbuchsee, Switzerland; c Clavaseptin, Vetoquinol AG, Ittigen, Switzerland; d Metronidazol B. Braun, B. Braun Medical AG, Sempach, Switzerland; e Dexatat, Dr. E. Graeub AG, Bern, Switzerland; f Prednisolon Streuli, G. Streuli & Co. AG, Uznach, Switzerland; g Sintenyl i.v. 0.5 mg, Sintetica S.A., Mandrisio, Switzerland; h Ketasol, Dr. E. Graeub AG, Bern, Switzerland; i Temgesic, Essex Pharma GmbH, Munich, Germany; j Tramadol-Mepha 50 retard, Mepha Pharma AG, Aesch, Switzerland; k Omeprazol-Teva, Teva Pharma AG, Aesch, Switzerland; l Ulcogant Suspension, Merck Serono GmbH, Darmstadt, Germany; m Paspertin, Abbott, Altishofen, Switzerland; n Anzemet, Sanofi-Aventis; Meyrin, Switzerland; o Plasma-Lyte A, Baxter AG, Volketswil, Switzerland.