Review Article

Nontuberculous Mycobacteria in Saudi Arabia and Gulf Countries: A Review

Table 4

Summary of the main NTM species identified worldwide.

Region/countryMain NTM species% of total isolatesNTM diversityYearsClinical relevance/commentsOverall trend

Europe/England (review) [35]M. avium-intracellulare42.915 species were identified and two isolates were not properly identified.1995–2006Pulmonary and extrapulmonary diseases.Increase in SGM.
M. malmoense13.7
M. kansasii12.5
Others

Europe/Italy (review) [34]M. avium42.913 species were identified, an increasing proportion of unidentified species.2004–201476.2% of clinical isolates were extracted from pulmonary specimens.Increase in SGM.
M. intracellulare14.3
M. gordonae11.6
Others

America/USA (article) [36]MAC40.922 species were identified.2001–200917% were pulmonary cases and the remaining were due to extrapulmonary infections.Increase in SGM.
M. gordonae28.7
M. abscessus4.5
Others

America/Canada (article) [95]MAC62Not clearly stated but approximately 8 species.1997–2003 and 2007Mainly pulmonary infections.Increase in SGM.
M. xenopi23

Australia/Queensland (article) [37]MAC7215 species were identified.1999–2005Pulmonary and extrapulmonary infections.Increase in SGM.
M. kansasii8

Asia/China (article) [39]M. kansasii4525 species were identified.2007–2012Mainly pulmonary cases.Increase in SGM.
M. intracellulare20.8
M. chelonae/abscessus14.9
Others

Asia/South Korea (article) [40]MAC5310 species were identified and 2.5% unidentified.2001–2011Mainly pulmonary.Increase in RGM.
M. abscessus-massiliense25
M. fortuitum6
Others

Asia/India (article) [38]M. abscessus31.313 species were identified.2013–201579.8% pulmonary and 18.2% extrapulmonary.Increase in RGM.
M. fortuitum22
M. intracellulare13.9
M. chelonae9.1
Others

Middle East/GCC State (articles) [1721]M. fortuitum29A total of 18 species were identified from clinical specimens, though data remain scarce.1991–2013Pulmonary and extrapulmonary.Increase in RGM.
MAC25
M. abscessus17
Others

Africa/Zambia (articles) [42, 96]M. lentiflavum34Not very clear but approximately 18 species were identified.2015 and March to August 2001Mainly pulmonary.Not very clear.
MAC15

M. avium complex (MAC), Gulf Cooperation Council (GCC), rapidly growing mycobacteria (RGM), and slowly growing mycobacteria (SGM).