Research Article
Assessing Survival and Grading the Severity of Complications in Octogenarians Undergoing Pulmonary Lobectomy
Table 4
SBRT: comparative Data.
| | Author | Years of enrollment | Total Gy (fractions) | | Age (median) | Clinical stages included | Follow-up (median months) | Complications (NCI-CTC grade) | 3-year primary tumor control rate | 3-year local and regional control | 3-year rate of disseminated failure | DFS | Overall Survival | Predictors of poor survival ( value) |
| | Nagata et al. [6] | 1998–2004 | 48 (4) | 45 | 51–87 | Stage I:
T1N0M0
T2N0M0 | 30 | 4% (2) | — | — | — | 3 year
IA 72%
IB 71% | 3 year
IA 83%
IB 72% | — |
| | Dales et al. [28] | 2006–2009 | 54 (3) | 55 | 48–89 (72) | Stage I:
T1N0M0
T2N0M0 | 34.4 | 12.7% (3)
3.6% (4) | 97.6% | 87.2% | 22.1% | 3 year 48.3% | 3 year
55.8% (median 48.1 mo) | — |
| | Matsuo et al. [24] | 1999–2005 | 48 (4) | 66 | 67–86 (76.5) | Stage I:
T1aN0M0
T1bN0M0
T2aN0M0 | 35.9 | — | — | — | — | 5 year
33.8% | 5 year 44.6% (median 35.9 mo) | — |
| | Fakiris et al. [5] | — | 60–66 (3) | 70 | | T1N0M0
T2N0M0 | 50.2 | 8.6% (3)
1.4% (4)
7.1% (5) | 88.1% | — | — | — | 3 year 42.7% (median 32.4 mo) | — |
| | Timmerman et al. [29] | 2004–2007 | 48 (4) | 65 | 50–91 (median 89) | T1N0M0 | 45.4 | 9.2% (3) | — | — | — | — | 3 year 76% | — |
| | Nagata et al. [30] | 1999–2007 | — | 875 | 75–97 | Stage I:
T1N0M0
T2N0M0 | — | — | — | — | — | — | — | — |
| | Palma et al. [31] | 1995–2004 | 100–141 Gy | 87 | 74 | Stage I:
T1N0M0
T2N0M0 | 55 | 1.1% | — | — | — | — | 5 yr 72% (S1a), 62% (S1b) | — |
| | Current Study | 2004–2012 | — | 45 | ≥80 (mean 82) | Stages I–IIIA | 53 | 62% overall, severe 17% Seely grade ≥IIIB | — | — | — | — | 5 year 52% | — |
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