Canadian Respiratory Journal

Research Article

Comparison of Different Disease-Specific Health-Related Quality of Life Measurements in Patients with Long-Term Noninvasive Ventilation

Table 4

Results of multiple regression analyses.


	SRI summary		MRF-26 total		SGRQ total


Model I (excluding patient-reported measurements)
BMI, kg/m²	—	—	−0.27	0.09
FEV₁, % predicted					−0.31	0.09
FVC, % predicted	—	—	−0.38	0.16	—	—
PaCO₂, kPa	−0.31	0.15	—	—
BE, mmol/L	—	—	—	—

Cumulative		0.15		0.25		0.09

Model II (including patient-reported measurements)
BMI, kg/m²	—	—	−0.17	0.05
FEV₁, % predicted					—	—
FVC, % predicted	—	—	—	—	—	—
PaCO₂, kPa	—	—	—	—
BE, mmol/L	—	—	—	—
mMRC dyspnea	−0.45	0.27	0.55	0.37	0.63	0.46
HADS depression	−0.49	0.34	0.37	0.24	0.29	0.17

Cumulative		0.61		0.67		0.63

All values represent coefficient of determination (). Missing values (—) indicate no significant relationships; SRI = Severe Respiratory Insufficiency; MRF = Maugeri Respiratory Failure; SGRQ = St. George’s Respiratory Questionnaire; BMI = body mass index; FEV₁ = forced expiratory volume in one second; FVC = forced vital capacity; PaO₂ = arterial oxygen pressure; PaCO₂ = arterial carbon dioxide pressure; BE = base excess; mMRC = modified Medical Research Council; HADS = Hospital Anxiety and Depression Scale.