Canadian Respiratory Journal

Research Article

Metabolomics in COPD Acute Respiratory Failure Requiring Noninvasive Positive Pressure Ventilation

Table 1

Subjects characteristics.


	Stable COPD (n = 15)	AECOPD (n = 12)	CHF (n = 8)	PNA (n = 9)

Age, y ± SD	68 ± 10.1	73.1 ± 10.6	78.5 ± 9.1	65.7 ± 17.3
Female, % (n)	60% (9)	66.6% (8)	62.5% (5)	33.3% (3)
BMI, kg/m² ± SD	29.25 ± 5.7	28.8 ± 5.3	29.1 ± 8.6	29.8 ± 9.5
FEV1% predicted	44.7 ± 13.3	47.4 ± 10.6	NA	NA
Duration of NIPPV, d ± SD	NA	4.9 ± 3.4	1.8 ± 0.8	7.2 ± 4.7
Intubation, % (n)	NA	8.3% (1)	25% (2)	11.1% (1)
ICU LOS, d ± SD	NA	5 ± 3.9	6 ± 8.6	6.2 ± 5
ICU mortality, % (n)	NA	8.3% (1)	25% (2)	33.3% (3)
Hospital LOS, d ± SD	NA	6.1 ± 4.1	8 ± 8.8	9.8 ± 4.3
Hospital mortality, % (n)	NA	8.3% (1)	25% (2)	33.3% (3)
Discharge home, % (n)	NA	66.6% (8)	50% (4)	33.3% (3)

Available FEV1% predicted only for 6 subjects. AECOPD = acute exacerbation of COPD, BMI = body mass index, CHF = heart failure, LOS = length of stay, NIPPV = noninvasive positive pressure ventilation, PNA = pneumonia.