Serial Observations and Mutational Analysis of an Adoptee with Family History of Hypertrophic Cardiomyopathy

Figure 1

Pedigree of the adoptee. The proband is highlighted by the arrow. The proband carries two sequence variations within the MYH7 (cardiac beta-myosin heavy chain gene): 2156G>A (R719Q) change in exon 19 (marked by a shaded area on upper left hand corner), and 4537A>T (T1513S) on exon 33 (the shaded area on the lower left hand corner). Cardiac hypertrophy is marked by shaded area on upper right-hand corner). SCD: sudden cardiac death. ICD: internal cardiac defibrillator placed (dot).