Strategies in the Surgical Management of Atrial Fibrillation

Table 5

Freedom from AF following atrial size reduction.

Reference	Group	Procedure**	Duration of Pre op AF (months)	𝑛	Atrial diameter (mm)		Followup (months)	Freedom from AF
					Pre op	Post op
Wang et al., [68]	ELA	Modified full RF Cox Maze III + biatrial reduction procedure with reef imbricate technique	45 ± 87	83	64 ± 12	49 ± 8	19 ± 16 (Last f/u)	90% at last f/u
	GLA		56 ± 67	39	86 ± 17	51 ± 11		58% at last f/u
Scherer et al., [67]	Study	LA reduction procedure + RF Maze III	>12	20	60 ± 15	57 ± 5	36 (Last f/u)	70.0%
	Control	RF Maze III only	>12	20	69 ± 19	55 ± 6		61.1%
Badhwar et al., [69]		RF Maze III + LA reduction	49.3 ± 58	70	67 ± 12	43 ± 6	10.7 ± 8.4 (Mean f/u)	92.6% at 0–6/12; 93.8% at 7–12/12; 92% at 1 year
Marui et al., [66]	Study	Cryoablation modified LA maze III + volume reduction	169.2 ± 64.8	44	67.1 ± 7.8	47.6 ± 6.3	36 (Last f/u)	90% at 12/12; 87% at 24/12; 100% at 36/12
	Control	Cryoablation modified LA maze III only	114 ± 61.2	36	64.5 ± 6.7	62.1 ± 7.9		69% at 12/12; 67% at 24/12; 64% at 36/12
Scherer et al., [70]		LA reduction	>12	27	60.2 ± 9.8	44.5 ± 7.0	12 (Last f/u)	63% at 1 year*
García-Villarreal et al., [71]		LA reduction	46.8 ± 34.8	23	81 ± 14.7	48 ± 7.7	13.9 ± 11 (Mean f/u)	100% at last f/u
Sankar and Farnsworth, [72]		MV replacement + CABG + LA reduction	228	1	69	41	7	Pt remained in SR at last f/u

*19% of patients described as “free from AF at 1 year” suffered from intermittent, symptomatic pAF during the 1-year followup period.
**All patients underwent concomitant MV ± TV ± AV procedures ± CABG at the time of procedure outlined.