Research Article
Effect of Exercise Training on Interleukin-6, Tumour Necrosis Factor Alpha and Functional Capacity in Heart Failure
Table 1
Studies identified in PUBMED, MEDLINE search.
| | Study | Subjects(Control) | Year | Cytokines measured | %∆ VO2 | Mode of Exercise |
| | Adamapoulos et al. [23] | 12 | 2001 | Soluble adhesion molecules | 13 | Home bike | | Adamopoulos et al. [12] | 24 | 2002 | TNF-alpha, Interleukin-6 | 15 | Home bike | | Conraads et al. [16] | 23 (12) | 2002 | TNF-alpha, Interleukin-6 | 7.5 | Bike and resistance training | | Ferraz et al. [21]# | 30 (10) | 2004 | TNF-alpha, Interleukin-6 | 23 | Bike | | Gielen et al. [2] | 20 (10) | 2003 | TNF-alpha, Interleukin-1, 6 and beta
In both serum and skeletal muscle | 29 | Bike | | Karavidas et al. [24] | 16 (8) | 2006 | TNF-alpha, Interleukin-6, 10 | 7.5* | Electrical stimulation | | Larsen et al. [22]# | 28 | 2001 | TNF-alpha, Interleukin-6,8 | 8* | Aerobic endurance training and home bike | | Larsen et al. [25] | 25 | 2008 | Plasma Chromogranin A (CgA) | 8* | Aerobic endurance training and home bike | | Laoutaris et al. [26] | 38 | 2007 | TNF-alpha, Interleukin-6 | 12 | Low versus high intensity inspiratory muscle training | | LeMaitre et al. [17]# | 46 | 2004 | TNF-alpha, Interleukin-6 | 3 | Bike and electrical stimulation | | Niebauer et al. [27] | 18 (9) | 2005 | TNF-alpha Interleukin-6, e-selectin | 11 | Bike | | Smart [28]# | 22 | 2008 | TNF-alpha, Interleukin-6, brain natriurietic peptide (BNP) | 20 | Bike | | Xu et al. [18] | 60 (28) | 2002 | TNF-alpha | Unknown | Unknown |
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*% change in 6-minute walk distance (Peak VO2 not measured). #Study used in this paper.
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