The Association of the Metabolic Syndrome with PAI-1 and t-PA Levels

Table 2

PAI-1 antigen levels (ng/mL) for the association of the metabolic syndrome and other covariates.

	Median (IQR)	Univariate models	Multivariable model
Age at baseline		<0.001	<0.001
<40 yrs	51 (32, 89)
40–60 yrs	72 (42, 123)
>60 yrs	80 (47, 138)
Gender		<0.001	<0.001
Male	75 (46, 132)
Female	59 (34, 107)
BMI		<0.001	<0.001
<25 kg/m^2 (%)	49 (31, 79)
25–30 kg/m^2 (%)	80 (49, 143)
>30 kg/m^2 (%)	115 (71, 189)
Smoking status		<0.001	<0.001
Current/former	70 (43, 126)
Nonsmokers	64 (37, 114)
C-reactive protein		<0.001	0.633
≥3.0 mg/L	84 (45, 152)
<3.0 mg/L	63 (38, 109)
Urinary albumin excretion		<0.001	0.303
<30 mg/24 h (%)	66 (39, 116)
30–300 mg/24 h (%)	80 (48, 154)
>300 mg/24 h (%)	104 (68, 134)
Insulin levels		<0.001	<0.001
<8 μU/mL (%)	52 (34, 82)
8–12 μU/mL (%)	77 (44, 128)
>12 μU/mL (%)	114 (71, 181)
Metabolic syndrome		<0.001	<0.001
Present	126 (81, 194)
Absent	59 (36, 103)

PAI-1 levels were missing in 29 (1.2%) of subjects.