Right Ventricular Dysfunction and Failure in Chronic Pressure Overload
Figure 1
Regional heterogeneity of RV remodeling and dysfunction observed in patients with pulmonary hypertension. Patients were divided into one of three groups based upon hemodynamic parameters: Normal (normal pulmonary artery [PA] pressure, defined as mean PA pressure ≤25 mmHg), PH-C (PH with hemodynamically compensated RV function, defined as mean PA pressure >25 mmHg and right atrial [RA] pressure <10 mmHg), and PH-D (PH with hemodynamically decompensated RV function, defined as mean PA pressure ≥25 mmHg, and RA pressure ≥10 mmHg). (a) Regional RV wall thickness in end diastole (ED, filled symbols) and end systole (ES, open symbols). (b) Corresponding fractional wall thickening. * PH-C versus Normal or PH-D versus Normal; † PH-D versus PH-C, from [25].
