Dyssynchrony Assessment with Tissue Doppler Imaging and Regional Volumetric Analysis by 3D Echocardiography Do Not Predict Long-Term Response to Cardiac Resynchronization Therapy
Table 5
Correlation between left ventricular dyssynchrony indices by QRS duration, TDI, and 3D volumetric analysis in patients undergoing CRT.
Pearson’s correlation coefficient
QRS duration (ms)
TDI: septal-to- lateral delay
TDI: Tf-Ts 6 basal segments (ms)
TDI: Tf-Ts 12 basal segments (ms)
3D: SD of Tmsv in 12 segments as % of R-R interval
3D: SD of Tmsv in 16 segments as % of R-R interval
QRS duration (ms)
Cor. coeff.
1
0.3
0.6
0.7
0.05
0.1
P-value
0.07
<0.05
<0.05
0.8
0.5
TDI: Septal-to-lateral delay
Cor. coeff.
0.3
1
0.6
0.6
0.06
0.03
P-value
0.07
<0.05
<0.05
0.7
0.8
TDI: Tf-Ts 6 basal segments (ms)
Cor. coeff.
0.6
0.6
1
0.8
0.05
0.2
P-value
<0.05
<0.05
<0.05
0.7
0.2
TDI: Tf-Ts 12 basal segments (ms)
Cor. coeff.
0.7
0.6
0.8
1
0.03
0.1
P-value
<0.05
<0.05
<0.05
0.8
0.5
3D: SD of Tmsv in 12 segments as % of R-R interval
Cor. coeff.
0.05
0.06
0.05
0.03
1
0.8
P-value
0.8
0.7
0.7
0.8
<0.05
3D: SD of Tmsv in 16 segments as % of R-R interval
Cor. coeff.
0.1
0.03
0.2
0.1
0.8
1
P-value
0.5
0.8
0.2
0.5
<0.05
CRT: cardiac resynchronization therapy, TDI: tissue Doppler imaging, Tf-Ts: difference in time to peak systolic velocity between the fastest and slowest LV segments, Tmsv: difference in longest and shortest time to minimal systolic volume in LV segments, SD: standard deviation, Cor. Coeff.: correlation coefficient.
