Progression of Left Ventricular Dysfunction and Remodelling under Optimal Medical Therapy in CHF Patients: Role of Individual Genetic Background

Table 4

Genetic predictors of echocardiographic changes at one year followup (univariate and multivariate analyses, see text for details).

Genotypes	Univariate analysis  P-value			Multivariate analysis  P-value
	ΔLVEF	ΔLVEDV	ΔLVESV	ΔLVEF	ΔLVEDV	ΔLVESV
ACE II versus. ID/DD	NS	NS	.003	—	.03	.028
β1AR389 ≥ 1Arg versus GlyGly	.02	.02	NS	.03	NS	.02
β 2AR16 GlyGly versus ≥ 1Arg	.05	.05	NS	NS	NS	NS
β 2AR27 GlnGln versus ≥ 1Glu	NS	NS	NS	NS	NS	NS

Abbreviations as in Table 1.