Bicuspid Aortic Valve Disease and Ascending Aortic Aneurysms: Gaps in Knowledge

Table 1

Prevalence of BAV in previously published investigations.

Author(s)	Study population (𝑛)	BAV prevalence (%)	Male : female	Study type	Age; (mean ± SD)
Lewis and Grant [1]	215	1.39	3 : 1	Necropsy	—
Wauchope [2]	9966 (6124 males, 3842 females)	0.5	3 : 1	Necropsy	33.6 ± 20.1
Roberts [3]	1,440	0.9	3 : 1	Necropsy	46; (15–79 years)
Larson and Edwards [4]	21,417	1.37	—	Necropsy	—
Datta et al. [5]	8,800	0.59	11 : 1	Necropsy	35.5; (8–70 years)
Pauperio et al. [6]	2,000 (1,499 males, 501 females)	0.65	All males	Necropsy	40.5 ± 20.4; (3 mo–68 years)
Basso et al. [7]	817 (400 males, 417 females)	0.5	3 : 1	2D TTE	Primary school children
Tutar et al. [8]	1,075 (567 males, 508 females)	0.46	4 : 1	2D TTE	Gestational age; 38.2 ± 1.9 weeks
Nistri et al. [9]	20,946 (all males)	0.8	N/A	2D TTE	18 ± 2 years