Research Article
Omega-3 Status and the Relationship between Plasma Asymmetric Dimethylarginine and Risk of Myocardial Infarction in Patients with Suspected Coronary Artery Disease
Table 4
Risk of acute myocardial infarction for the upper decile of ADMA in strata of TFAs and n-3 PUFA.
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ALA: α-linolenic acid; CI: confidence interval; DHA: docosahexaenoic acid; DPA: docosapentaenoic acid; EPA: eicosapentaenoic acid; HR: hazard ratio; n-3 PUFAs: omega-3 polyunsaturated fatty acids; TFAs: total fatty acids; n-3 LCPUFAs: long chain omega-3 polyunsaturated fatty acids; wt%: percentage by weight. 1P interaction. 2Model 1: hazard ratios of acute myocardial infarction for plasma ADMA > 90th percentile with plasma ADMA levels < 90th percentile as reference. The model included age (continuous), sex, acute coronary syndrome (yes/no), diabetes mellitus (yes/no), hypertension (yes/no), current smoking (yes/no), extend of coronary artery disease (0–3), left ventricular ejection fraction (continuous). 3Model 2: hazard ratios of acute myocardial infarction for plasma ADMA levels > 90th percentile with plasma ADMA levels < 90th percentile as reference. The model included age (continuous), sex, acute coronary syndrome (yes/no), diabetes mellitus (yes/no), hypertension (yes/no), current smoking (yes/no), extend of coronary artery disease (0–3), left ventricular ejection fraction (continuous), hypercholesterolemia (yes/no), HbA1c (continuous), and glomerular filtration rate (continuous). 4Combination of ALA, EPA, DPA, and DHA. 5Combination of EPA, DPA, and DHA. |